Effect of Aes-103 Anti-Sickling Agent On Oxygen Affinity and Stability of Red Blood Cells From Patients with Sickle Cell Anemia

被引：1
|
作者：
Mendelsohn, Laurel G. [1 ]
Pedoeim, Leah [1 ]
van Beers, Eduard J. [1 ]
Saiyed, Rehan [1 ]
Nichols, James S. [1 ]
Wang, Xunde [1 ]
Kato, Gregory J. [1 ]
机构：
[1] NHLBI, Sickle Cell Vasc Dis Sect, Hematol Branch, Bethesda, MD USA
来源：
BLOOD | 2012年 / 120卷 / 21期
关键词：
D O I：
10.1182/blood.V120.21.85.85
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
85
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Quantification of Anti-Sickling Effect of Aes-103 in Sickle Cell Disease Using an in Vitro Microfluidic Assay
    Du, E.
    Mendelsohn, Laurel
    Nichols, James S.
    Dao, Ming
    Kato, Gregory J.
    BLOOD, 2014, 124 (21)
  • [2] The Anti-Sickling Agent Aes-103 Decreases Sickle Erythrocyte Fragility, Hypoxia-Induced Sickling and Hemolysis In Vitro
    Mendelsohn, Laurel G.
    Pedoeim, Leah
    Wang, Yekai Kevin
    Saiyed, Rehan
    Brantner, Christine A.
    Daniels, Mathew P.
    Nichols, James S.
    Wang, Xunde
    van Beers, Eduard J.
    Kato, Gregory J.
    BLOOD, 2013, 122 (21)
  • [3] Interactions of an Anti-Sickling Drug with Hemoglobin in Red Blood Cells from a Patient with Sickle Cell Anemia
    Strader, Michael Brad
    Liang, Hongying
    Meng, Fantao
    Harper, Julia
    Ostrowski, David A.
    Henry, Eric R.
    Shet, Arun S.
    Eaton, William A.
    Thein, Swee L.
    Alayash, Abdu I.
    BIOCONJUGATE CHEMISTRY, 2019, 30 (03) : 568 - 571
  • [4] Safety of Short-Term Valacyclovir as an Anti-Sickling Agent in Sickle-Cell Anemia
    Ender, Katherine L.
    DeBellis, Robert H.
    Erlanger, Bernard F.
    Billote, Genia B.
    Brittenham, Gary M.
    PEDIATRIC BLOOD & CANCER, 2011, 56 (05) : 843 - 845
  • [5] ANTI-SICKLING EFFECT OF DIETARY THIOCYANATE IN PROPHYLACTIC CONTROL OF SICKLE-CELL-ANEMIA
    AGBAI, O
    JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION, 1986, 78 (11) : 1053 - 1056
  • [6] In-vitro anti-sickling and membrane stability potentials of Mishenland polyherbal extract on sickle red blood cells
    Oyenike, Musiliu A.
    Akpan, Helen B.
    Otulana, Olatoye J.
    Adefule, Adebayo K.
    Adedokun, Kamoru A.
    Oluogun, Waheed A.
    Muhibi, Musa A.
    Ojokuku, Hammed O.
    EGYPTIAN JOURNAL OF HAEMATOLOGY, 2019, 44 (01): : 65 - 71
  • [7] ASE 1, FIRST-IN-MAN, DOSE-RESPONSE STUDY OF AES-103 (5-HMF), AN ANTI-SICKLING, ALLOSTERIC MODIFIER OF HEMOGLOBIN OXYGEN AFFINITY IN HEALTHY NORMAL VOLUNTEERS
    Stern, Warren
    Mathews, David
    McKew, John
    Seiler, Stephen R.
    Shen, Xiqgiang
    Kato, Gregory J.
    AMERICAN JOURNAL OF HEMATOLOGY, 2013, 88 (12) : E79 - E79
  • [8] GBT440, a Potent Anti-Sickling Hemoglobin Modifier Reduces Hemolysis, Improves Anemia and Nearly Eliminates Sickle Cells in Peripheral Blood of Patients with Sickle Cell Disease
    Lehrer-Graiwer, Josh
    Howard, Jo
    Hemmaway, Claire Jane
    Awogbade, Moji
    Telfer, Paul
    Layton, Mark
    Mant, Timothy
    Dufu, Kobina
    Hutchaleelaha, Athiwat
    Koller, Teri
    Oksenberg, Donna
    Patel, Mira
    Ramos, Eleanor
    BLOOD, 2015, 126 (23)
  • [9] Effects of Hypoxic Red Blood Cells on Sickling Kinetics of Red Blood Cells From Patients With Sickle Cell Disease
    Sowemimo-Coker, Samuel O.
    Kuypers, Frans
    Larkin, Sandra
    Tung, Gloria
    Dunham, Andrew
    TRANSFUSION, 2019, 59 : 157A - 157A
  • [10] The Effect of Antioxidants on the Properties of Red Blood Cells From Patients With Sickle Cell Anemia
    Al Balushi, Halima
    Hannemann, Anke
    Reese, David
    Brewin, John
    Gibson, John Stanley
    FRONTIERS IN PHYSIOLOGY, 2019, 10
12345