Recent Advances in the Application of Metabolomics for Nutrition and Health

被引:44
|
作者
Gonzalez-Pena, Diana [1 ]
Brennan, Lorraine [1 ]
机构
[1] Univ Coll Dublin, Inst Food & Hlth, Sch Agr & Food Sci, Dublin 4, Ireland
基金
欧洲研究理事会; 欧盟地平线“2020”;
关键词
metabolomics; dietary biomarkers; personalized nutrition; metabotypes; SPECTROMETRY-BASED METABOLOMICS; RANDOMIZED CONTROLLED-TRIAL; HUMAN URINARY BIOMARKERS; FREE-LIVING POPULATION; NMR-BASED METABOLOMICS; WHOLE GRAIN RYE; BLACK TEA; DIETARY PATTERNS; SYSTEMS BIOLOGY; PROLINE BETAINE;
D O I
10.1146/annurev-food-032818-121715
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Metabolomics is the study of small molecules called metabolites in biological samples. Application of metabolomics to nutrition research has expanded in recent years, with emerging literature supporting multiple applications. Key examples include applications of metabolomics in the identification and development of objective biomarkers of dietary intake, in developing personalized nutrition strategies, and in large-scale epidemiology studies to understand the link between diet and health. In this review, we provide an overview of the current applications and identify key challenges that need to be addressed for the further development of the field. Successful development of metabolomics for nutrition research has the potential to improve dietary assessment, help deliver personalized nutrition, and enhance our understanding of the link between diet and health.
引用
收藏
页码:479 / 519
页数:41
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