Attacking MALT1 for ABC-DLBCL therapy

被引:0
|
作者
Krappmann, Daniel [1 ]
机构
[1] German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Res Unit Cellular Signal Integrat, Inst Mol Toxicol & Pharmacol, Neuherberg, Germany
关键词
PROTEASE;
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:1489 / 1490
页数:2
相关论文
共 50 条
  • [1] Harnessing MALT1 inhibition for rational combinatorial therapy of ABC-DLBCL
    Fontan, Lorena
    Yang, Chenghua
    Kabaleeswaran, Venkataraman
    Volpon, Laurent
    Osborne, Michael
    Beltran, Elena
    Rosen, Monica
    Shaknovich, Rita
    Yang, Shao N.
    Gascoyne, Randy D.
    Cerchietti, Leandro
    Martinez-Climent, Jose A.
    Glickman, J. Fraser
    Borden, Katherine
    Wu, Hao
    Melnick, Ari
    CANCER RESEARCH, 2014, 74 (19)
  • [2] Antiapoptotic properties of MALT1 protease are associated with redox homeostasis in ABC-DLBCL cells
    Zhu, Leqing
    Tang, Fen
    Lei, Zhiwei
    Guo, Chengbin
    Song, Yueqi
    Huang, Junqing
    Xia, Xichun
    MOLECULAR CARCINOGENESIS, 2019, 58 (12) : 2340 - 2352
  • [3] MALT1 Small Molecule Inhibitors Specifically Suppress ABC-DLBCL In Vitro and In Vivo
    Fontan, Lorena
    Yang, Chenghua
    Kabaleeswaran, Venkataraman
    Volpon, Laurent
    Osborne, Michael J.
    Beltran, Elena
    Garcia, Monica
    Cerchietti, Leandro
    Shaknovich, Rita
    Yang, Shao Ning
    Fang, Fang
    Gascoyne, Randy D.
    Angel Martinez-Climent, Jose
    Glickman, J. Fraser
    Borden, Katherine
    Wu, Hao
    Melnick, Ari
    CANCER CELL, 2012, 22 (06) : 812 - 824
  • [4] Search for Novel MALT1 inhibitors by using ABC-DLBCL and GCB-DLBCL cell lines
    Son, Y.
    Park, C.
    Choi, S.
    MOLECULAR BIOLOGY OF THE CELL, 2015, 26
  • [5] Pyrazolopyrimidines as novel selective allosteric MALT1 inhibitors with in vivo activity in ABC-DLBCL
    Weiss, Andreas
    Radimerski, Thomas
    Wyss, Daniel
    Andraos, Rita
    Buhles, Alexandra
    Sterker, Dario
    Quancard, Jean
    Pissot, Carole
    Simic, Oliver
    Bigaud, Marc
    Bornancin, Frederic
    Schlapbach, Achim
    Regnier, Catherine
    McSheehy, Paul
    Buchdunger, Elisabeth
    Wartmann, Markus
    Renatus, Martin
    Endres, Ralf
    Sellers, William
    Hofmann, Francesco
    CANCER RESEARCH, 2018, 78 (13)
  • [6] MALT1 Phosphorylation Controls Activation of T Lymphocytes and Survival of ABC-DLBCL Tumor Cells
    Gehring, Torben
    Erdmann, Tabea
    Rahm, Marco
    Gras, Carina
    Flatley, Andrew
    O'Neill, Thomas J.
    Woods, Simone
    Meininger, Isabel
    Karayel, Ozge
    Kutzner, Kerstin
    Grau, Michael
    Shinohara, Hisaaki
    Lammens, Katja
    Feederle, Regina
    Hauck, Stefanie M.
    Lenz, Georg
    Krappmann, Daniel
    CELL REPORTS, 2019, 29 (04): : 873 - +
  • [7] Pharmacologic Inhibition of MALT1 Protease by Phenothiazines as a Therapeutic Approach for the Treatment of Aggressive ABC-DLBCL
    Nagel, Daniel
    Spranger, Stefani
    Vincendeau, Michelle
    Grau, Michael
    Raffegerst, Silke
    Kloo, Bernhard
    Hlahla, Daniela
    Neuenschwander, Martin
    von Kries, Jens Peter
    Hadian, Kamyar
    Doeken, Bernd
    Lenz, Peter
    Lenz, Georg
    Schendel, Dolores J.
    Krappmann, Daniel
    CANCER CELL, 2012, 22 (06) : 825 - 837
  • [8] Identification of MALT1 feedback mechanisms enables rational design of potent antilymphoma regimens for ABC-DLBCL
    Fontan, Lorena
    Goldstein, Rebecca
    Casalena, Gabriella
    Durant, Matthew
    Teater, Matthew R.
    Wilson, Jimmy
    Phillip, Jude
    Xia, Min
    Shah, Shivem
    Us, Ilkay
    Shinglot, Himaly
    Singh, Ankur
    Inghirami, Giorgio
    Melnick, Ari
    BLOOD, 2021, 137 (06) : 788 - 800
  • [9] MALT1 inhibition as an anchor for combinatorial therapy of ABC-DLBCL.
    Fontan, Lorena
    Yang, Chenghua
    Shinglot, Himaly
    Kabaleeswaran, Venkataraman
    Laurent, Volpon
    Osborne, Michael
    Beltran, Elena
    Rosen, Monica
    Shaknovich, Rita
    Yang, Shao N.
    Gascoyne, Randy D.
    Cerchietti, Leandro
    MArtinez-Climent, Jose A.
    Glickman, J. Fraser
    Borden, KAtherine
    Wu, Hao
    Melnick, Ari
    CLINICAL CANCER RESEARCH, 2015, 21
  • [10] Substrate-mimetic covalent inhibitor of MALT1 is most effective against CARD11 mutant ABC-DLBCL
    Fontan, Lorena
    Scott, David
    Hatcher, John
    Qiao, Qi
    Us, Ilkay
    Casalena, Gabriella
    Bekkers, Mariette
    Philippar, Ulrike
    Durant, Matthew
    Chennamadhavuni, Spandan
    Wu, Hao
    Gray, Nathaniel
    Melnick, Ari
    CANCER RESEARCH, 2017, 77