A compact biological cell irradiation system with a Van de Graaff accelerator

被引:2
|
作者
Cho, I. C. [1 ]
Niu, H. [2 ]
Chen, C. H. [3 ,4 ]
Chou, W. T. [1 ]
Yu, Y. C. [5 ]
Hsu, C. H. [1 ]
机构
[1] Natl Tsing Hua Univ, Dept Biomed Engn & Environm Sci, Hsinchu, Taiwan
[2] Natl Tsing Hua Univ, Nucl Sci & Technol Dev Ctr, Hsinchu, Taiwan
[3] Natl Chiao Tung Univ, Ctr Nano Sci & Technol, Hsinchu, Taiwan
[4] Natl Chiao Tung Univ, Microelect & Informat Syst Res Ctr, Hsinchu, Taiwan
[5] Acad Sinica, Inst Phys, Taipei 115, Taiwan
关键词
Accelerator; Ion beam applications; Biological effect of radiation; CHARGED-PARTICLE MICROBEAM;
D O I
10.1016/j.nimb.2013.03.042
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
This report describes the development of a compact microcell irradiation system in the 3 MV MN Van de Graaff accelerator in the Accelerator Laboratory of National Tsing Hua University (NTHU). The main feature of this system is backscattering, a technique whereby a 100 nm gold scattering foil is placed in the center of a scattering chamber, instead of a 90 bending magnet. The incident particles produced by the accelerator bombard the scattering foil and scatter isotropically. A set of micro pinholes was installed above the scattering foil and directed the 90 scattering particles to irradiate the cell target. This innovation simplifies the system design and massively reduces the cost and space requirements for system construction. (C) 2013 Elsevier B.V. All rights reserved.
引用
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页码:360 / 363
页数:4
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