FRET-based ratiometric fluorescent probes for selective Fe3+ sensing and their applications in mitochondria

被引:60
|
作者
Chen, Wen-dan [1 ]
Gong, Wei-tao [1 ]
Ye, Zhi-qiang [2 ]
Lin, Yuan [1 ]
Ning, Gui-ling [1 ]
机构
[1] Dalian Univ Technol, Sch Chem Engn, State Key Lab Fine Chem, Dalian 116024, Peoples R China
[2] Dalian Univ Technol, Sch Chem, State Key Lab Fine Chem, Dalian 116024, Peoples R China
基金
中国国家自然科学基金;
关键词
FRIEDREICHS-ATAXIA; ENERGY-TRANSFER; ZN2+ SENSOR; CU2+ SENSOR; IRON; HG2+; ION; CHEMOSENSORS; CONJUGATE; FE(III);
D O I
10.1039/c3dt50832c
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Efficient ratiometric fluorescent Fe3+ probes were designed and synthesized by linking a conjugated naphthalene chromophore to a rhodamine platform and a lipophilic triphenylphosphonium (TPP) cation. The probes could sensitively and selectively detect mitochondrial Fe3+ in living cells.
引用
收藏
页码:10093 / 10096
页数:4
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