A Systematic Study on the Self-Assembly Behaviour of Multi Component Fmoc-Amino Acid-Poly(oxazoline) Systems

被引：5
|
作者：
Caponi, Pier-Francesco [1 ]
Ulijn, Rein V. [2 ]
机构：
[1] Univ Jena, Lab Organ & Macromol Chem IOMC, D-07745 Jena, Germany
[2] Univ Strathclyde, Dept Pure & Appl Chem, WestCHEM, Glasgow G1 1XL, Lanark, Scotland
来源：
POLYMERS | 2012年 / 4卷 / 03期
关键词：
responsive polymers; amino acids; enzyme responsive materials; RING-OPENING POLYMERIZATION; FLUORESCENCE; PYRENE; 2-ETHYL-2-OXAZOLINE; LIPOSOMES;
D O I：
10.3390/polym4031399
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
We report a systematic study of a modular approach to create multi-component supramolecular nanostructures that can be tailored to be both enzyme and temperature responsive. Using a straightforward synthetic approach we functionalised a thermal responsive polymer, poly(2-isopropyl-2-oxazoline), with fluorenylmethoxycarbonyl-amino acids that drive the self-assembly. Depending on the properties of appended amino acids, these polymers undergo substantial morphological changes in response to the catalytic action of alkaline phosphatase.
引用
收藏
页码：1399 / 1415
页数：17
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