Effects of cytotoxicity of erythromycin on PAH-degrading strains and degrading efficiency

被引:0
|
作者
Huang, Ying [1 ]
Yang, Chen [1 ,2 ,3 ]
Li, Yiyi [1 ]
Guo, Chuling [1 ,2 ]
Dang, Zhi [1 ,2 ]
机构
[1] South China Univ Technol, Coll Environm & Energy, Guangzhou 510006, Guangdong, Peoples R China
[2] Minist Educ, Key Lab Pollut Control & Ecosyst Restorat Ind Clu, Guangzhou 510006, Guangdong, Peoples R China
[3] South China Univ Technol, Guangzhou Higher Educ Mega Ctr, Guangdong Prov Engn & Technol Res Ctr Environm Re, Guangzhou 510006, Peoples R China
来源
RSC ADVANCES | 2016年 / 6卷 / 115期
基金
中国国家自然科学基金;
关键词
POLYCYCLIC AROMATIC-HYDROCARBONS; SPHINGOMONAS SP GY2B; PYRENE DEGRADATION; RESISTANCE GENES; MYCOBACTERIUM SP; ANTIBIOTICS; BACTERIA; TETRACYCLINE; CIPROFLOXACIN; STREPTOMYCIN;
D O I
10.1039/c6ra23957a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The toxicity and degradation effects of erythromycin on a phenanthrene degrading strain of Sphingomonas sp. GY2B and a pyrene degrading strain of Mycobacterium gilvum CP13 were investigated. The minimum inhibitory concentration (MIC) of erythromycin to GY2B was 0.25 mg L-1, but the MIC of erythromycin to CP13 was 16 mg L-1. Total superoxide dismutase (SOD) activity and lactate dehydrogenase (LDH) activity were significantly reduced when the erythromycin concentration exceeded the MIC. Erythromycin also reduced the growth of the strains and the biodegradation of polycyclic aromatic hydrocarbons (PAHs). Addition of erythromycin decreased GY2B phenanthrene removal efficiency by 0.81-86.03% compared to the control. Erythromycin also reduced CP13 pyrene degradation. The lowest pyrene removal efficiency was 10.78% when the erythromycin concentration was 256 mg L-1. The toxicity of erythromycin inhibited the growth of both GY2B and CP13.
引用
收藏
页码:114396 / 114404
页数:9
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