Innate immune responses to Chlamydia pneumoniae infection: role of TLRs, NLRs, and the inflammasome

被引：35
|
作者：
Shimada, Kenichi [2 ]
Crother, Timothy R. [2 ]
Arditi, Moshe [1 ,2 ]
机构：
[1] Univ Calif Los Angeles, Infect & Immunol Dis Res Ctr, Div Pediat Infect Dis & Immunol, Cedars Sinai Med Ctr, Los Angeles, CA 90048 USA
[2] Univ Calif Los Angeles, David Geffen Sch Med, Los Angeles, CA 90048 USA
来源：
MICROBES AND INFECTION | 2012年 / 14卷 / 14期
基金：
美国国家卫生研究院;
关键词：
Chlamydia pneumoniae; TLR; NLR; Inflammasome; ELECTRON-MICROSCOPIC OBSERVATIONS; PEPTIDOGLYCAN SYNTHESIS; SIGNALING PATHWAYS; III SECRETION; CYTOCHROME-C; IFN-GAMMA; TRACHOMATIS; MITOCHONDRIA; ATHEROSCLEROSIS; ACTIVATION;
D O I：
10.1016/j.micinf.2012.08.004
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Chlamydiae are important human pathogens that are responsible for a wide rage of diseases with a significant impact on public health. In this review article we highlight how recent studies have increased our knowledge of Chlamydia pneumoniae pathogenesis and mechanisms of innate immunity directed host defense against C. pneumoniae infection. (C) 2012 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：1301 / 1307
页数：7
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