RECURRENT LOSS OF FUNCTION OF THE SETD2 GENE IN AGGRESSIVE SYSTEMIC MASTOCYTOSIS AND MAST CELL LEUKEMIA

被引：0
|
作者：
Soverini, S.
Mancini, M.
De Benedittis, C.
Zazzeroni, L.
Papayannidis, C.
Guadagnuolo, V.
Calogero, R.
Zago, E.
Scandola, A.
Garonzi, M.
Savini, P.
Pagano, L.
Zanotti, R.
Perbellini, O.
Bonadonna, P.
Specchia, G.
Merante, S.
Elena, C.
Gangemi, D.
Grifoni, F. I.
Ferrarini, A.
Delledonne, M.
Valent, P.
Cavo, M.
Rondoni, M.
Martinelli, G.
机构：
[1] Univ Bologna, Hematol LeA Seragnoli, Bologna, Italy
[2] Univ Turin, Turin, Italy
[3] Personal Genom Srl, Verona, Italy
[4] Univ Verona, I-37100 Verona, Italy
[5] Osped Infermi, Faenza, Italy
[6] Univ Cattolica S Cuore, Rome, Italy
[7] Hematol Unit, Verona, Italy
[8] Allergy Unit, Verona, Italy
[9] Univ Bari, Bari, Italy
[10] Hematol Unit, Pavia, Italy
[11] Fdn IRCCS Policlin San Matteo, Pavia, Italy
[12] Hematol Unit, Frosinone, Italy
[13] Univ Milan, Dept Hematol, Milan, Italy
[14] Med Univ Vienna, Vienna, Austria
来源：
HAEMATOLOGICA | 2015年 / 100卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
P140
引用
收藏
页码：110 / 111
页数：2
相关论文
共 50 条
  • [1] Inactivation of the SETD2 Tumor Suppressor Gene in Mast Cell Leukemia
    Soverini, Simona
    De Benedittis, Caterina
    Rondoni, Michela
    Mancini, Manuela
    Papayannidis, Cristina
    Guadagnuolo, Viviana
    Leo, Elisa
    Zazzeroni, Luca
    Calogero, Raffaele
    Zago, Elisa
    Scandola, Anna
    Garonzi, Marianna
    Ferrarini, Alberto
    Savini, Paolo
    Quercia, Oliviero
    Pagano, Livio
    Zanotti, Roberta
    Perbellini, Omar
    Specchia, Giorgina
    Merante, Serena
    Elena, Chiara
    Gangemi, Domenica
    Poletti, Giovanni
    Delledonne, Massimo
    Cerny-Reiterer, Sabine
    Cavo, Michele
    Valent, Peter
    Martinelli, Giovanni
    BLOOD, 2014, 124 (21)
  • [2] Integrated molecular characterization of mast cell leukemia reveals recurrent inactivation of the SETD2 tumor suppressor gene
    Soverini, Simona
    De Benedittis, Caterina
    Rondoni, Michela
    Mancini, Manuela
    Papayannidis, Cristina
    Zazzeroni, Luca
    Guadagnuolo, Viviana
    Zago, Elisa
    Griggio, Francesca
    Ferrarini, Alberto
    Garonzi, Marianna
    Delledonne, Massimo
    Specchia, Giorgina
    Zanotti, Roberta
    Perbellini, Omar
    Pagano, Livio
    Cavo, Michele
    Valent, Peter
    Martinelli, Giovanni
    CANCER RESEARCH, 2015, 75
  • [3] SETD2 Loss of Function Is a Recurrent Event in Advanced-Phase Chronic Myeloid Leukemia
    Mancini, Manuela
    De Santis, Sara
    Monaldi, Cecilia
    Bavaro, Luana
    Martelli, Margherita
    Castagnetti, Fausto
    Gugliotta, Gabriele
    Rosti, Gianantonio
    Iurlo, Alessandra
    Abruzzese, Elisabetta
    Salvucci, Marzia
    Pregno, Patrizia
    Gozzini, Antonella
    Crugnola, Monica
    Albano, Francesco
    Bonifacio, Massimiliano
    Calistri, Elisabetta
    Tiribelli, Mario
    Binotto, Gianni
    Imovilli, Annalisa
    Trabacchi, Elena
    Galimberti, Sara
    Barate, Claudia
    Tenti, Elena
    Baccarani, Michele
    Cavo, Michele
    Martinelli, Giovanni
    Soverini, Simona
    BLOOD, 2017, 130
  • [4] SETD2 IS A BONA FIDE TUMOR SUPPRESSOR IN SYSTEMIC MASTOCYTOSIS
    Mancini, M.
    Monaldi, C.
    De Santis, S.
    Papayannidis, C.
    Rondoni, M.
    Sartor, C.
    Bruno, S.
    Curti, A.
    Zanotti, R.
    Bonifacio, M.
    Scaffidi, L.
    Pagano, L.
    Criscuolo, M.
    Ciceri, F.
    Elena, C.
    Tosi, P.
    Valent, P.
    Cavo, M.
    Soverini, S.
    HAEMATOLOGICA, 2022, 107 : 42 - 42
  • [5] SETD2 NON-GENOMIC LOSS OF FUNCTION IN ADVANCED SYSTEMIC MASTOCYTOSIS (SM): PATHOGENETIC AND THERAPEUTIC IMPLICATIONS
    Mancini, M.
    Monaldi, C.
    De Santis, S.
    Papayannidis, C.
    Rondoni, M.
    Abbenante, M. C.
    Bavaro, L.
    Martelli, M.
    Ficarra, E.
    Paciello, G.
    Fontana, M. C.
    Manfrini, M.
    Zanotti, R.
    Pagano, L.
    Albano, F.
    Ciceri, F.
    Elena, C.
    Tosi, P.
    Delledonne, M.
    Valent, P.
    Cavo, M.
    Martinelli, G.
    Soverini, S.
    HAEMATOLOGICA, 2018, 103 : S48 - S48
  • [6] Establishment of a murine model of aggressive systemic mastocytosis/mast cell leukemia
    Demehri, S
    Corbin, A
    Loriaux, M
    Druker, BJ
    Deininger, MW
    EXPERIMENTAL HEMATOLOGY, 2006, 34 (03) : 284 - 288
  • [7] MDM2 and Aurora Kinase a Contribute to SETD2 Loss of Function in Advanced Systemic Mastocytosis: Implications for Pathogenesis and Treatment
    Mancini, Manuela
    Monaldi, Cecilia
    De Santis, Sara
    Papayannidis, Cristina
    Rondoni, Michela
    Bavaro, Luana
    Martelli, Margherita
    Chiara, Abbenante Maria
    Curti, Antonio
    Ficarra, Elisa
    Paciello, Giulia
    Fontana, Maria Chiara
    Zanotti, Roberta
    Bonifacio, Massimiliano
    Scaffidi, Luigi
    Pagano, Livio
    Criscuolo, Marianna
    Albano, Francesco
    Ciceri, Fabio
    Elena, Chiara
    Tosi, Patrizia
    Delledonne, Massimo
    Avanzato, Carla
    Xumerle, Luciano
    Valent, Peter
    Martinelli, Giovanni
    Cavo, Michele
    Soverini, Simona
    BLOOD, 2018, 132
  • [8] Treatment of Patients with Aggressive Systemic Mastocytosis, Mast Cell Leukemia and Mast Cell Sarcoma: A Single Center Experience
    Gleixner, Karoline V.
    Valent, Peter
    Sperr, Wolfgang R.
    BLOOD, 2018, 132
  • [9] SYSTEMIC MASTOCYTOSIS MAST-CELL LEUKEMIA
    NEWHOOK, CJ
    NEW ZEALAND MEDICAL JOURNAL, 1981, 93 (686) : 444 - 444
  • [10] Recurrent SETD2 Mutations in T-Cell Large Granular Lymphocytic Leukemia
    Plowman, R.
    Li, Jingwei
    Mason, Frank
    Lindsley, R.
    Mason, Emily
    Kim, Annette
    LABORATORY INVESTIGATION, 2022, 102 (SUPPL 1) : 1001 - 1002
12345