DNA Binding Properties of Water-Soluble Mixed Ligand Nickel(II) Complex with Calf-thymus DNA Using Different Instrumental Methods

被引：12
|
作者：
Bordbar, Maryam [1 ]
Tabatabaee, Masoumeh [2 ]
Faal, Ali Yeganeh [3 ]
Lighvan, Zohreh Mehri [4 ]
Fazaeli, Razieh [5 ]
机构：
[1] Univ Qom, Fac Sci, Dept Chem, Qom, Iran
[2] Islamic Azad Univ, Dept Chem, Yazd Branch, Yazd, Iran
[3] Payam Noor Univ, Dept Chem, Tehran, Iran
[4] Isfahan Univ Technol, Dept Chem, Esfahan, Iran
[5] Islamic Azad Univ, Dept Chem, Shahreza Branch, Shahreza, Iran
来源：
SYNTHESIS AND REACTIVITY IN INORGANIC METAL-ORGANIC AND NANO-METAL CHEMISTRY | 2015年 / 45卷 / 12期
关键词：
nickel complex; partial intercalation binding; methylene blue; calf-thymus DNA; CRYSTAL-STRUCTURE; BIOLOGICAL-ACTIVITY; ETHIDIUM-BROMIDE; METAL-COMPLEXES; METHYLENE-BLUE; NUCLEIC-ACIDS; FLUORESCENCE; RUTHENIUM(II); SEMICARBAZONE; SPECTROSCOPY;
D O I：
10.1080/15533174.2014.900627
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The binding ability of the a water-soluble nickel(II) complex with pyridine-2,6-dicarboxylic acid (pydcH(2)) and 2-aminopyrimidine (amp) formulated as [Ni(pydc)(amp)]center dot 2H(2)O]center dot H2O (1) to calf-thymus (CT-DNA) was investigated. The binding ability of 1 was studied by measuring the effects on the electronic absorption spectra, thermal denaturation studies, fluorescence quenching studies by using methylene blue (MB) as a fluoresce probe, and circular dichroism (CD) spectra. All the results suggest the interaction modes between 1 and DNA were partial intercalation with a binding constant of (8.43 +/- 0.2) x 10(4) M-1.
引用
收藏
页码：1882 / 1888
页数：7
相关论文
共 50 条
  • [1] A Supramolecular Interaction of a Ruthenium Complex With Calf-Thymus DNA: A Ligand Binding Approach by NMR Spectroscopy
    Crizostomo Kock, Flavio Vinicius
    Costa, Analu Rocha
    de Oliveira, Katia Mara
    Batista, Alzir Azevedo
    Ferreira, Antonio Gilberto
    Venancio, Tiago
    [J]. FRONTIERS IN CHEMISTRY, 2019, 7
  • [2] Interaction studies of water-soluble Zn(II) complex with calf thymus DNA using biophysical and molecular docking methods"
    Shahabadi, Nahid
    Ghaffari, Lida
    Mardani, Zahra
    Shiri, Farshad
    [J]. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2024, 43 (06): : 493 - 516
  • [3] Nickel(II)-naproxen mixed-ligand complexes: synthesis, structure, antioxidant activity and interaction with albumins and calf-thymus DNA
    Totta, Xanthippi
    Hatzidimitriou, Antonios G.
    Papadopoulos, Athanasios N.
    Psomas, George
    [J]. NEW JOURNAL OF CHEMISTRY, 2017, 41 (11) : 4478 - 4492
  • [4] Interaction Studies of a Novel, Water-Soluble and Anti-Cancer Palladim(II) Complex with Calf Thymus DNA
    Mansouri-Torshizi, H.
    Saeidifar, M.
    Divsalar, A.
    Saboury, A. A.
    Shahraki, S.
    [J]. BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2010, 31 (02) : 435 - 441
  • [5] A spectroscopic study on Calf thymus DNA binding properties of nickel (II) complex with imidazole derivatives of 1,10-phenanthroline ligand
    Khouzani, Alireza Amini
    Sohrabi, Nasrin
    Rasouli, Nahid
    Moghadam, Mahboube Eslami
    [J]. IRANIAN CHEMICAL COMMUNICATION, 2018, 6 (01) : 30 - 38
  • [6] Synthesis of a new Pt(II) complex containing valganciclovir drug and calf-thymus DNA interaction study using multispectroscopic methods
    Shahabadi, Nahid
    Fatahi, Somaye
    Maghsudi, Maryam
    [J]. JOURNAL OF COORDINATION CHEMISTRY, 2018, 71 (02) : 258 - 270
  • [7] Synthesis, structure, and calf-thymus DNA binding of ternary fleroxacin-Cu(II) complexes
    Xiao, Ying
    Xu, Kailin
    Wang, Qing
    Xiong, Xinnuo
    Huang, Yanmei
    Li, Hui
    [J]. RSC ADVANCES, 2016, 6 (83) : 80286 - 80295
  • [8] Experimental and Molecular Docking Studies on the Interaction of a Water-Soluble Pd(II) Complex Containing β-Amino Alcohol with Calf Thymus DNA
    Nahid Shahabadi
    Lida Ghaffari
    Zahra Mardani
    Farshad Shiri
    [J]. Biological Trace Element Research, 2022, 200 : 1988 - 2000
  • [9] Experimental and Molecular Docking Studies on the Interaction of a Water-Soluble Pd(II) Complex Containing β-Amino Alcohol with Calf Thymus DNA
    Shahabadi, Nahid
    Ghaffari, Lida
    Mardani, Zahra
    Shiri, Farshad
    [J]. BIOLOGICAL TRACE ELEMENT RESEARCH, 2022, 200 (04) : 1988 - 2000
  • [10] Binding affinities of Schiff base Fe(II) complex with BSA and calf-thymus DNA: Spectroscopic investigations and molecular docking analysis
    Rudra, Suparna
    Dasmandal, Somnath
    Patra, Chiranjit
    Kundu, Arjama
    Mahapatra, Ambikesh
    [J]. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2016, 166 : 84 - 94
12345