Synthesis, Self-Association, and Solubilizing Ability of an Amphiphilic Derivative of Poly(ethylene glycol) Methyl Ether

被引:1
|
作者
Pashirova, T. N. [1 ,2 ]
Burilova, E. A. [1 ]
Lukashenko, S. S. [1 ]
Lenina, O. A. [1 ]
Zobov, V. V. [1 ]
Khamatgalimov, A. R. [1 ,2 ]
Kovalenko, V. I. [1 ,2 ]
Zakharova, L. Ya [1 ,2 ]
Sinyashin, O. G. [1 ,2 ]
机构
[1] Russian Acad Sci, Arbuzov Inst Organ & Phys Chem, Kazan Sci Ctr, Ul Arbuzova 8, Kazan 420088, Tatarstan, Russia
[2] Kazan Natl Res Technol Univ, Ul Karla Marksa 68, Kazan 420015, Tatarstan, Russia
基金
俄罗斯科学基金会;
关键词
methoxy(polyethoxy)ethyl stearate; surfactant; self-association; solubilization; piperine; DRUG-DELIVERY SYSTEMS; ANTITUMOR EFFICACY; CIRCULATION TIME; GRAFTING DENSITY; BLACK PEPPER; NANOPARTICLES; STEALTH; LIPOSOMES; PIPERINE; PEGYLATION;
D O I
10.1134/S107036321712012X
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A new amphiphilic derivative-methoxy(polyethoxy)ethyl stearate has been synthesized with the goal of creating therefrom systems for delivery and enhancement of bioavailability of piperine. The aggregation and solubilizing properties of omega-methylpoly(oxyethylene) stearate have been studied by means of a set of physicochemical methods.
引用
收藏
页码:2832 / 2837
页数:6
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