Selective axillary surgery in breast cancer patients based on positron emission tomography with 18F-fluoro-2-deoxy-D-glucose:: Not yet!

被引：52
|
作者：
Guller, U
Nitzsche, EU
Schirp, U
Viehl, CT
Torhorst, J
Moch, H
Langer, I
Marti, WR
Oertli, D
Harder, F
Zuber, M [1 ]
机构：
[1] Kantonsspital Olten, Dept Surg, CH-4600 Olten, Switzerland
[2] Univ Basel, Dept Surg, Basel, Switzerland
[3] Univ Basel, Dept Radiol, Inst Nucl Med, Basel, Switzerland
[4] Univ Basel, Inst Pathol, Basel, Switzerland
来源：
BREAST CANCER RESEARCH AND TREATMENT | 2002年 / 71卷 / 02期
关键词：
F-18-fluoro-2-deoxy-D-glucose; positron emission tomography; invasive breast cancer; micrometastases; sentinel lymph node;
D O I：
10.1023/A:1013828710301
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
We prospectively evaluated 31 patients with invasive breast cancer. Preoperative positron emission tomography (PET) with F-18-fluoro-2-deoxy-D-glucose (F-18-FDG) for detection of axillary lymph node metastases was compared with the histopathologic status of the sentinel lymph node (SLN). Sensitivity of PET imaging was 43%, specificity and negative predictive value were 94 and 67%, respectively. The smallest metastasis detected by PET measured 3 mm in diameter. The results of this study suggest that detection of small axillary lymph node metastases is limited by the currently achievable spatial resolution of PET imaging. Selective axillary surgery in breast cancer patients based on F-18-FDG PET is yet not possible.
引用
收藏
页码：171 / 173
页数：3
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