Pulmonary inflammatory pseudotumor due to Coxiella burnetii. Case report and literature review

被引:11
|
作者
Polo, M. F. [1 ]
Mastrandrea, S. [1 ]
Santoru, L. [1 ]
Arcadu, A. [1 ]
Masala, G. [2 ]
Marras, V. [3 ]
Bagella, G. [1 ]
Sechi, M. M. [1 ]
Tanda, F. [3 ]
Pirina, P. [1 ]
机构
[1] Univ Sassari, Dept Clin & Expt Med, I-07100 Sassari, Italy
[2] Expt Zooprophylact Inst Sardinia, Sassari, Italy
[3] Univ Sassari, Inst Pathol, Dept Biomed Sci, I-07100 Sassari, Italy
关键词
Pulmonary pseudotumor; Infection; Coxiella burnetii; CHRONIC Q-FEVER; LUNG; DIAGNOSIS; TUMOR;
D O I
10.1016/j.micinf.2015.08.008
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
A 58-year-old man was admitted because of respiratory failure, episodic fever with chilling, cough, malaise, fatigue, myalgia and weight loss lasting for at least one month. Chest x-rays and CT scan of the chest showed bilateral pulmonary consolidations in upper lobes, the left lower lobe, and mediastinal lymphadenopathy. Bronchoscopy with cytology was unremarkable. A needle CT-guided lung biopsy documented an inflammatory pseudotumor, lymphoplasmacytic type. Serology showed high titer antibodies to phase II Coxiella burnetii infection. Therapy with doxycycline and hydroxychloroquine for three months led to a complete resolution of symptoms and radiological findings, and a marked decrease in titers to Q fever. (C) 2015 Published by Elsevier Masson SAS on behalf of Institut Pasteur.
引用
收藏
页码:795 / 798
页数:4
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