Synthesis, characterization, swelling and drug release behavior of semi-interpenetrating network hydrogels of sodium alginate and polyacrylamide

被引：217

作者：

Samanta, Himadri Sekhar ^{[1
]}

Ray, Samit Kumar ^{[1
]}

机构：

[1] Univ Calcutta 92, Dept Polymer Sci & Technol, Kolkata 700009, India

来源：

CARBOHYDRATE POLYMERS | 2014年 / 99卷

关键词：

Sodium alginate; Acrylamide; Semi-IPN hydrgels; Characterization; Drug release; SUPERABSORBENT HYDROGELS; SUPERPOROUS HYDROGELS; POLYMER NETWORKS; REMOVAL; DYES; PARAMETERS; DELIVERY; METHACRYLATE); ACRYLATE); COPOLYMER;

D O I：

10.1016/j.carbpol.2013.09.004

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Several semi interpenetrating network (SIPN) type hydrogels were synthesized by in-situ free radical crosslink copolymerization of acrylamide and crosslinker N,N'-methylene bisacrylamide (MBA) in aqueous solution of sodium alginate (SA). These SIPN hydrogels were characterized by FTIR, NMR SEM, DTA-TGA, XRD, PZC and also by swelling characteristics and network parameters. Adsorption (loading) and release of acetaminophen drug were studied with these hydrogels. Solution pH, crosslinker concentration and monomer to SA weight ratio of the hydrogels were found to have a strong effect on adsorption and in vitro release profile of the drug from the gel matrix. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：666 / 678

页数：13

共 50 条

[1] Silk fibroin/polyacrylamide Semi-interpenetrating network hydrogels for controlled drug release
Mandal, Biman B.
Kapoor, Sonia
Kundu, Subhas C.
[J]. BIOMATERIALS, 2009, 30 (14) : 2826 - 2836
[2] Gelation and swelling behavior of semi-Interpenetrating Polymer Network hydrogels based on polyacrylamide and poly(vinyl alcohol)
Aalaie, Jamal
Vasheghani-Farahani, Ebrahim
Semsarzadeh, Mohammad Ali
Rahmatpour, Ali
[J]. JOURNAL OF MACROMOLECULAR SCIENCE PART B-PHYSICS, 2008, 47 (05): : 1017 - 1027
[3] New semi-interpenetrating network hydrogels: Synthesis, characterization and properties
Zhao, San-Ping
Ma, Dong
Zhang, Li-Ming
[J]. MACROMOLECULAR BIOSCIENCE, 2006, 6 (06) : 445 - 451
[4] Synthesis of silver nanocomposite semi-interpenetrating polymer network hydrogel based on sodium alginate-g-polyacrylamide for using in Epirubicin anticancer drug release
Bardajee, Ghasem Rezanejade
Dianatnejad, Nastaran
Mahmoodi, Nosrat O.
Ghasemzadeh, Hossein
[J]. JOURNAL OF POLYMER RESEARCH, 2024, 31 (07)
[5] Rheological and swelling behavior of semi-interpenetrating networks of polyacrylamide and scleroglucan
Aalaie, Jamal
Rahmatpour, Ali
Vasheghani-Farahani, Ebrahim
[J]. POLYMERS FOR ADVANCED TECHNOLOGIES, 2009, 20 (12) : 1102 - 1106
[6] Synthesis and characterization of sodium alginate/acrylamide semi-interpenetrating polymer networks
Solpan, D
Torun, M
[J]. JOURNAL OF APPLIED POLYMER SCIENCE, 2006, 100 (01) : 335 - 342
[7] Preparation and Properties of Carboxymethyl Chitosan and Sodium Alginate Semi-interpenetrating Hydrogels
Cui, Li
Jia, Jun-fang
Xiong, Zi-hao
Zhang, Chuan-jie
Ye, Zheng-tao
Zhu, Ping
[J]. ACTA POLYMERICA SINICA, 2014, (03): : 361 - 368
[8] Biodegradable sodium alginate-based semi-interpenetrating polymer network hydrogels for antibacterial application
Rao, K. Madhusudana
Rao, K. S. V. Krishna
Ramanjaneyulu, G.
Rao, K. Chowdoji
Subha, M. C. S.
Ha, Chang-Sik
[J]. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2014, 102 (09) : 3196 - 3206
[9] Semi-interpenetrating network of acrylamide-grafted-sodium alginate microspheres for controlled release of diclofenac sodium, preparation and characterization
AL-Kahtani, Ahmed A.
Sherigara, B. S.
[J]. COLLOIDS AND SURFACES B-BIOINTERFACES, 2014, 115 : 132 - 138
[10] WOOD HEMICELLULOSE/CHITOSAN-BASED SEMI-INTERPENETRATING NETWORK HYDROGELS: MECHANICAL, SWELLING AND CONTROLLED DRUG RELEASE PROPERTIES
Karaaslan, Ahmet M.
Tshabalala, Mandla A.
Buschle-Diller, Gisela
[J]. BIORESOURCES, 2010, 5 (02): : 1036 - 1054

← 1 2 3 4 5 →