Disclosing the nature of thermo-responsiveness of poly(N-isopropyl acrylamide)-based polymeric micelles: aggregation or fusion?

被引:18
|
作者
Wang, Fangyingkai [1 ]
Du, Jianzhong [1 ,2 ]
机构
[1] Tongji Univ, Sch Mat Sci & Engn, Key Lab Adv Civil Engn Mat, Minist Educ, Shanghai 201804, Peoples R China
[2] Tongji Univ, Sch Med, Shanghai Peoples Hosp 10, Shanghai 200072, Peoples R China
基金
中国国家自然科学基金;
关键词
CROSS-LINKED MICELLES; CONTROLLED-RELEASE; HOMOPOLYMER VESICLES; COPOLYMER MICELLES; DIBLOCK COPOLYMER; BLOCK-COPOLYMER; CHAINS; NANOPARTICLES; MORPHOLOGY; MEMBRANE;
D O I
10.1039/c5cc02641e
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The apparent size increase of poly(N-isopropyl acrylamide) ( PNIPAM)-based polymericmicelles upon heating was usually ascribed to their volume growth or aggregation in aqueous solution. Herein we designed a photo-cross-linkable PNIPAM-based copolymer and proposed another thermo-responsive behaviour - fusion, which is disclosed by transmission electron microscopy (TEM) after in situ fixing morphologies at desired temperatures.
引用
收藏
页码:11198 / 11201
页数:4
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