miRNAs in endothelial cell signaling: The endomiRNAs

被引：31
|
作者：
Santoro, Massimo M. [1 ]
Nicoli, S. [2 ]
机构：
[1] Univ Turin, Ctr Mol Biotechnol, Dept Mol Biotechnol & Hlth Sci, Turin, Italy
[2] Yale Univ, Yale Cardiovasc Reseach Ctr, New Haven, CT USA
来源：
EXPERIMENTAL CELL RESEARCH | 2013年 / 319卷 / 09期
关键词：
miRNA; Development; Signaling; Endothelial cell; Angiogenesis; VASCULAR INTEGRITY; TARGETED DELETION; MICRORNA MIR-126; ANGIOGENESIS; EXPRESSION; MIR-221; BIOGENESIS; COMPLEX; DICER; MICE;
D O I：
10.1016/j.yexcr.2012.12.009
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
microRNAs (miRNAs) have a pivotal role during the formation and function of the cardiovascular system. More than 300 miRNAs have been currently found within the mammalian genome, however only few specific miRNAs, named endomiRNAs, showed conseved endothelial cell expression and function. In this review we present an overview of the currently known endomiRNAs, focusing on their genome localization, processing and target gene repression during vasculogenesis and angiogenesis. Published by Elsevier Inc.
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收藏
页码：1324 / 1330
页数：7
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