DNA aptamer release from the DNA-SWNT hybrid by protein recognition

被引：8

作者：

Yoo, Chang-Hyuk ^{[1
,2
]}

Jung, Seungwon ^{[1
,2
,3
]}

Bae, Jaehyun ^{[4
,5
]}

Kim, Gunn ^{[6
]}

Ihm, Jisoon ^{[4
,5
]}

Lee, Junghoon ^{[1
,2
]}

机构：

[1] Seoul Natl Univ, Sch Mech & Aerosp Engn, Seoul 151742, South Korea

[2] Seoul Natl Univ, Intersemicond Res Ctr, Seoul 151742, South Korea

[3] Korea Inst Sci & Technol, Ctr Biomicrosyst, Seoul 136791, South Korea

[4] Seoul Natl Univ, FPRD, Seoul 151742, South Korea

[5] Seoul Natl Univ, Dept Phys & Astron, Seoul 151742, South Korea

[6] Sejong Univ, Dept Phys, Seoul 143747, South Korea

来源：

CHEMICAL COMMUNICATIONS | 2016年 / 52卷 / 13期

关键词：

CARBON NANOTUBE HYBRIDS; MOLECULES; SELECTION; DELIVERY; BINDING;

D O I：

10.1039/c5cc07726e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Here we show the formation of the complex between a DNA aptamer and a single-walled carbon nanotube (SWNT) and its reaction with its target protein. The aptamer, which is specifically bound with thrombin, the target protein in this study, easily wraps and disperses the SWNT by noncovalent pi-pi stacking.

引用

页码：2784 / 2787

页数：4

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