Towards a genetic AIDS vaccine

被引：1
|
作者：
Borderia, Antonia V. [1 ]
Berkhout, Ben [1 ]
机构：
[1] Univ Amsterdam, Lab Expt Virol, Ctr Infect Dis & Immunol Amsterdam CINIMA, Dept Med Microbiol,AMC, NL-1012 WX Amsterdam, Netherlands
来源：
RETROVIROLOGY | 2009年 / 6卷
关键词：
IMMUNODEFICIENCY-VIRUS TYPE-1; HIV; TRIAL; RNAI; CCR5;
D O I：
10.1186/1742-4690-6-93
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
We discuss a recent Nature Medicine publication by Philip Johnson and co-workers (Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys. Nat. Med. 2009, 15: 901-906) in which an effective HIV-1 vaccine was designed that is based on gene therapy. The introduced gene produces an antibody-like immunoadhesin in the blood that neutralizes the virus.
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页数：4
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