Advances in Microfluidic Biosensors Based on Luminescent Bacteria

被引:3
|
作者
Jin Xiao-Wei [1 ]
Li Zhe-Yu [1 ]
Xu Pian-Pian [1 ]
Zhang Xiao-Yan [1 ]
Ren Nan-Qi [1 ]
Kurilenko, Vitaliy V. [2 ]
Sun Kai [1 ]
机构
[1] Harbin Inst Technol, Sch Environm, State Key Lab Urban Water Resource & Environm, Harbin 150090, Heilongjiang, Peoples R China
[2] St Petersburg State Univ, Inst Earth Sci, St Petersburg 199034, Russia
基金
中国国家自然科学基金;
关键词
Luminescent bacteria; Acute toxicity; Environmental pollutant; Microfluidic; Biosensor; Review; ONLINE DETECTION; TOXICITY; PROMOTER;
D O I
10.19756/j.issn.0253-3820.181320
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Luminescent bacteria are a kind of bacteria which emit visible light at 450 nm - 490 nm. Its luminous intensity decreases with the increase of the concentration of toxic substances in test solution. The methods hased on luminescent bacteria are widely used in acute toxicity analysis of water quality because of its sensitiveness, quickness and inexpensiveness. With the rapid development of genetic modification technology, non-luminescent bacteria can also produce visible light by planting luminescent genes, which makes the application field of luminescent bacteria widen. In recent years, biosensors based on luminescent bacteria have attracted more and more attention, and the reports of bioluminescence biosensors based on microfluidic systems are increasing day by day. Based on the characteristics and mechanism of luminescent bacteria, this review introduced their applications in the environmental monitoring, and summarized several new bioluminescence sensors.
引用
收藏
页码:181 / 190
页数:10
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