223Ra-Dichloride Response Evaluation Using 18F-Fluciclovine PET/CT and Bone Scintigraphy in a Patient With Castration-Resistant Metastatic Prostate Cancer

被引：1
|
作者：
Wang, Jiaqiong [1 ]
Kuker, Russ [1 ]
Serafini, Aldo [1 ]
机构：
[1] Jackson Mem Hosp, Div Nucl Med, Dept Radiol, Miller Sch Med,Univ Miami Hosp, Miami, FL 33136 USA
来源：
CLINICAL NUCLEAR MEDICINE | 2020年 / 45卷 / 11期
关键词：
F-18-fluciclovine PET/CT; Ra-223-dichloride; Tc-99m-MDP; bone scan; prostate cancer; ACID; DIPHOSPHONATE; RADIUM-223; MECHANISMS; CELLS;
D O I：
10.1097/RLU.0000000000003168
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
A 66-year-old man was diagnosed with metastatic prostate cancer to the bones. The patient started(223)Ra-dichloride (Xofigo) therapy in April 2019.Tc-99m-MDP bone scan and(18)F-fluciclovine (Axumin) PET/CT showed discordant but overall complementary findings that indicated disease progression after 5 doses of Xofigo therapy. The patient's prostate-specific antigen increased from 33.81 ng/mL at baseline before Xofigo therapy and up to 394.3 ng/mL after the fifth dose of Xofigo treatment. Because of disease progression, Xofigo therapy was discontinued.
引用
收藏
页码：E486 / E488
页数：3
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