Natural killer cells: Stress out, turn on, tune in

被引：26

作者：

Diefenbach, A

Raulet, DH

机构：

[1] Univ Calif Berkeley, Dept Cell & Mol Biol, Berkeley, CA 94720 USA

[2] Univ Calif Berkeley, Canc Res Lab, Berkeley, CA 94720 USA

来源：

CURRENT BIOLOGY | 1999年 / 9卷 / 22期

关键词：

D O I：

10.1016/S0960-9822(00)80044-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Natural killer cells attack tumor cells, infected cells and some normal cells, but the basis of their specificity is not completely understood. Recent studies indicate that epithelial tumor cells upregulate a stress-induced MHC class-I-like protein termed MICA, triggering NK cells via a recently described receptor called NKG2D.

引用

页码：R851 / R853

页数：3

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