Study on improving blood flow with korean red ginseng substances using digital infrared thermal imaging and doppler sonography: randomized, double blind, placebo-controlled clinical trial with parallel design
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Kang, Jaehui
[1
]
Lee, Namhun
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Daejeon Univ, Cheonan Oriental Hosp, Dept Oriental Internal Med, Cheonan 330210, South KoreaDaejeon Univ, Cheonan Oriental Hosp, Dept Acupuncture & Moxibust, Cheonan 330210, South Korea
Lee, Namhun
[2
]
Ahn, Yochan
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Daejeon Univ, Dept Med Business, Taejon 300715, South KoreaDaejeon Univ, Cheonan Oriental Hosp, Dept Acupuncture & Moxibust, Cheonan 330210, South Korea
Ahn, Yochan
[3
]
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Lee, Hyun
[1
]
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[1] Daejeon Univ, Cheonan Oriental Hosp, Dept Acupuncture & Moxibust, Cheonan 330210, South Korea
[2] Daejeon Univ, Cheonan Oriental Hosp, Dept Oriental Internal Med, Cheonan 330210, South Korea
[3] Daejeon Univ, Dept Med Business, Taejon 300715, South Korea
Radix et rhizome ginseng rubra;
Blood circulation;
Body temperature;
Ultrasonography;
doppler;
Infrared thermal imaging;
Double-blind method;
PREVALENCE;
CELLS;
D O I:
10.1016/S0254-6272(13)60098-9
中图分类号:
R [医药、卫生];
学科分类号:
10 ;
摘要:
OBJECTIVE: To examine the efficacy of Korean red ginseng for improving blood flow in healthy people. METHODS: Participants were randomized and treated with 1500 mg of Korean red ginseng extract or placebo for 8 weeks. The effect of Korean red ginseng was evaluated by digital infrared thermal images, and Doppler sonography, and blood test. RESULTS: Forty subjects completed the protocol. Imbalance in local thermal distribution was significantly decreased in the Korean red ginseng group confirmed by digital infrared thermal images. Doppler sonography showed no significant change in maximum and average rates of blood circulation in single or complex areas. Blood analyses for coagulation and lipid metabolism factors revealed no significant changes. No abnormal reactions to the Korean red ginseng were observed. CONCLUSION: Digital infrared thermal imaging showed that the temperature deviation in the whole body decreased safely in the Korean red ginseng group, which mitigated the body-temperature imbalance. This result suggests that the Korean red ginseng improves blood circulation in the human body. (C) 2013 JTCM. All rights reserved.
机构:
Department of Oriental Internal Medicine,Cheonan Oriental Hospital of Daejeon UniversityDepartment of Acupuncture and Moxibustion, Cheonan Oriental Hospital of Daejeon University
Namhun Lee
Yochan Ahn
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Department of Medical Business, Daejeon UniversityDepartment of Acupuncture and Moxibustion, Cheonan Oriental Hospital of Daejeon University
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Shanghai Univ Tradit Chinese Med, Sch Pharm, Cai Lun Rd 1200, Shanghai, Peoples R ChinaShanghai Univ Tradit Chinese Med, Sch Pharm, Cai Lun Rd 1200, Shanghai, Peoples R China
Zhang, Li
Chen, Xiaoyun
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Shanghai Univ Tradit Chinese Med, LongHua Hosp, Dept Rheumatol, Shanghai, Peoples R ChinaShanghai Univ Tradit Chinese Med, Sch Pharm, Cai Lun Rd 1200, Shanghai, Peoples R China
Chen, Xiaoyun
Cheng, Yanqi
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Shanghai Univ Tradit Chinese Med, LongHua Hosp, Dept Rheumatol, Prevent & Hlth Care,Dept Tradit Chinese Med, South Wan Ping Rd 725, Shanghai, Peoples R ChinaShanghai Univ Tradit Chinese Med, Sch Pharm, Cai Lun Rd 1200, Shanghai, Peoples R China
Cheng, Yanqi
Chen, Qilong
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Shanghai Univ Tradit Chinese Med, Res Ctr TCM Complex Syst, Shanghai, Peoples R ChinaShanghai Univ Tradit Chinese Med, Sch Pharm, Cai Lun Rd 1200, Shanghai, Peoples R China
Chen, Qilong
Tan, Hongsheng
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Shanghai Univ Tradit Chinese Med, Sch Pharm, Cai Lun Rd 1200, Shanghai, Peoples R ChinaShanghai Univ Tradit Chinese Med, Sch Pharm, Cai Lun Rd 1200, Shanghai, Peoples R China
Tan, Hongsheng
Son, Dongwook
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Korea Ginseng Corp, Daejeon, South KoreaShanghai Univ Tradit Chinese Med, Sch Pharm, Cai Lun Rd 1200, Shanghai, Peoples R China
Son, Dongwook
Chang, Dongpill
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Korea Ginseng Corp, Daejeon, South KoreaShanghai Univ Tradit Chinese Med, Sch Pharm, Cai Lun Rd 1200, Shanghai, Peoples R China
Chang, Dongpill
Bian, Zhaoxiang
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Hong Kong Baptist Univ, Sch Chinese Med, Hong Kong Chinese Med Clin Study Ctr, Hong Kong, Peoples R ChinaShanghai Univ Tradit Chinese Med, Sch Pharm, Cai Lun Rd 1200, Shanghai, Peoples R China
Bian, Zhaoxiang
Fang, Hong
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Shanghai Univ Tradit Chinese Med, LongHua Hosp, Dept Rheumatol, Prevent & Hlth Care,Dept Tradit Chinese Med, South Wan Ping Rd 725, Shanghai, Peoples R ChinaShanghai Univ Tradit Chinese Med, Sch Pharm, Cai Lun Rd 1200, Shanghai, Peoples R China
Fang, Hong
Xu, Hongxi
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Shanghai Univ Tradit Chinese Med, Sch Pharm, Cai Lun Rd 1200, Shanghai, Peoples R ChinaShanghai Univ Tradit Chinese Med, Sch Pharm, Cai Lun Rd 1200, Shanghai, Peoples R China
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Conbio Technol Grp Co Ltd, Sci Res Ctr, Tianjin 300011, Peoples R ChinaConbio Technol Grp Co Ltd, Sci Res Ctr, Tianjin 300011, Peoples R China
Yang, Yi
Li, Jing
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Tianjin Third Cent Hosp, Lab Dept, Tianjin, Peoples R ChinaConbio Technol Grp Co Ltd, Sci Res Ctr, Tianjin 300011, Peoples R China
Li, Jing
Zhou, Shengyuan
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Tianjin Univ TCM, Prevent Treatment Dis Ctr, Affiliated Hosp 2, Tianjin, Peoples R ChinaConbio Technol Grp Co Ltd, Sci Res Ctr, Tianjin 300011, Peoples R China
Zhou, Shengyuan
Ni, Daoyan
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Tianjin Univ TCM, Prevent Treatment Dis Ctr, Affiliated Hosp 2, Tianjin, Peoples R ChinaConbio Technol Grp Co Ltd, Sci Res Ctr, Tianjin 300011, Peoples R China
Ni, Daoyan
Yang, Cailing
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CAIQTEST Beijing Co Ltd, Toxicol & Efficacy Evaluat Ctr, Beijing, Peoples R ChinaConbio Technol Grp Co Ltd, Sci Res Ctr, Tianjin 300011, Peoples R China
Yang, Cailing
Zhang, Xu
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Conbio Technol Grp Co Ltd, Sci Res Ctr, Tianjin 300011, Peoples R ChinaConbio Technol Grp Co Ltd, Sci Res Ctr, Tianjin 300011, Peoples R China
Zhang, Xu
Tan, Jian
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Conbio Technol Grp Co Ltd, Sci Res Ctr, Tianjin 300011, Peoples R ChinaConbio Technol Grp Co Ltd, Sci Res Ctr, Tianjin 300011, Peoples R China
Tan, Jian
Yan, Jingrui
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Conbio Technol Grp Co Ltd, Sci Res Ctr, Tianjin 300011, Peoples R ChinaConbio Technol Grp Co Ltd, Sci Res Ctr, Tianjin 300011, Peoples R China
Yan, Jingrui
Wang, Na
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Conbio Technol Grp Co Ltd, Sci Res Ctr, Tianjin 300011, Peoples R ChinaConbio Technol Grp Co Ltd, Sci Res Ctr, Tianjin 300011, Peoples R China
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Tianjin Third Cent Hosp, Hlth Management Ctr, Tianjin, Peoples R ChinaTianjin Third Cent Hosp, Hlth Management Ctr, Tianjin, Peoples R China
Yang, Yi
Wang, Hong
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Tianjin Third Cent Hosp, Gen Practice Dept, Tianjin, Peoples R ChinaTianjin Third Cent Hosp, Hlth Management Ctr, Tianjin, Peoples R China
Wang, Hong
Zhang, Ming
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Tianjin Third Cent Hosp, Nutr Dept, Tianjin, Peoples R ChinaTianjin Third Cent Hosp, Hlth Management Ctr, Tianjin, Peoples R China
Zhang, Ming
Shi, Mengxue
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Tianjin Third Cent Hosp, Hlth Management Ctr, Tianjin, Peoples R ChinaTianjin Third Cent Hosp, Hlth Management Ctr, Tianjin, Peoples R China
Shi, Mengxue
Yang, Cailing
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Chinese Acad Inspect & Quarantine, Food & Drug Safety Evaluat Ctr, Comprehens Testing Ctr, Beijing, Peoples R ChinaTianjin Third Cent Hosp, Hlth Management Ctr, Tianjin, Peoples R China
Yang, Cailing
Ni, Qiang
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Tianjin Third Cent Hosp, Hlth Management Ctr, Tianjin, Peoples R ChinaTianjin Third Cent Hosp, Hlth Management Ctr, Tianjin, Peoples R China
Ni, Qiang
Wang, Qi
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Tianjin Third Cent Hosp, Hlth Management Ctr, Tianjin, Peoples R ChinaTianjin Third Cent Hosp, Hlth Management Ctr, Tianjin, Peoples R China
Wang, Qi
Li, Jing
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Tianjin Third Cent Hosp, Lab Dept, Tianjin, Peoples R ChinaTianjin Third Cent Hosp, Hlth Management Ctr, Tianjin, Peoples R China
Li, Jing
Wang, Xuemei
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Conbio Technol Grp Co Ltd, Sci Res Ctr, Tianjin, Peoples R ChinaTianjin Third Cent Hosp, Hlth Management Ctr, Tianjin, Peoples R China
Wang, Xuemei
Zhang, Chen
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Conbio Technol Grp Co Ltd, Sci Res Ctr, Tianjin, Peoples R ChinaTianjin Third Cent Hosp, Hlth Management Ctr, Tianjin, Peoples R China
Zhang, Chen
Li, Zhi
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机构:
Conbio Technol Grp Co Ltd, Sci Res Ctr, Tianjin, Peoples R ChinaTianjin Third Cent Hosp, Hlth Management Ctr, Tianjin, Peoples R China
机构:
Kyung Hee Univ, Dept Internal Med, Coll Oriental Med, Seoul 130701, South KoreaKyung Hee Univ, Dept Internal Med, Coll Oriental Med, Seoul 130701, South Korea
Park, Jae-Woo
Lee, Beom-Joon
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Kyung Hee Univ, Dept Internal Med, Kangnam Korean Hosp, Seoul 135501, South KoreaKyung Hee Univ, Dept Internal Med, Coll Oriental Med, Seoul 130701, South Korea
Lee, Beom-Joon
Bu, Youngmin
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Kyung Hee Univ, Dept Herbal Pharmacol, Coll Oriental Med, Seoul 130701, South KoreaKyung Hee Univ, Dept Internal Med, Coll Oriental Med, Seoul 130701, South Korea
Bu, Youngmin
Yeo, Inkwon
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Sookmyung Womens Univ, Dept Stat, Seoul 140742, South KoreaKyung Hee Univ, Dept Internal Med, Coll Oriental Med, Seoul 130701, South Korea
Yeo, Inkwon
Kim, Jinsung
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Kyung Hee Univ, Dept Internal Med, Coll Oriental Med, Seoul 130701, South KoreaKyung Hee Univ, Dept Internal Med, Coll Oriental Med, Seoul 130701, South Korea
Kim, Jinsung
Ryu, Bongha
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Kyung Hee Univ, Dept Internal Med, Coll Oriental Med, Seoul 130701, South KoreaKyung Hee Univ, Dept Internal Med, Coll Oriental Med, Seoul 130701, South Korea
机构:
Korea Univ, Coll Med, Dept Psychiat, Seoul 136705, South KoreaKorea Univ, Coll Med, Dept Psychiat, Seoul 136705, South Korea
Yeo, Hye-Bin
Yoon, Ho-Kyoung
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Korea Univ, Coll Med, Dept Psychiat, Seoul 136705, South Korea
Korea Univ, Anam Hosp, Ctr Sleep Wake Disorders, Seoul 136705, South KoreaKorea Univ, Coll Med, Dept Psychiat, Seoul 136705, South Korea
Yoon, Ho-Kyoung
Lee, Heon-Jeong
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Korea Univ, Coll Med, Dept Psychiat, Seoul 136705, South Korea
Korea Univ, Anam Hosp, Ctr Sleep Wake Disorders, Seoul 136705, South KoreaKorea Univ, Coll Med, Dept Psychiat, Seoul 136705, South Korea
Lee, Heon-Jeong
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Kang, Seung-Gul
Jung, Ki-Young
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Korea Univ, Anam Hosp, Ctr Sleep Wake Disorders, Seoul 136705, South Korea
Korea Univ, Coll Med, Dept Neurol, Seoul 136705, South KoreaKorea Univ, Coll Med, Dept Psychiat, Seoul 136705, South Korea
Jung, Ki-Young
Kim, Leen
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Korea Univ, Coll Med, Dept Psychiat, Seoul 136705, South Korea
Korea Univ, Anam Hosp, Ctr Sleep Wake Disorders, Seoul 136705, South KoreaKorea Univ, Coll Med, Dept Psychiat, Seoul 136705, South Korea
机构:
Yonsei Univ, Severance Hosp, Coll Med, Dept Family Med, Seoul, South KoreaCatholic Univ Korea, Coll Med, St Vincents Hosp, Dept Family Med, Seoul, South Korea
Shim, Jae-Yong
Yoo, Byeong-Yeon
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Konyang Univ Hosp, Dept Family Med, Daejeon, South KoreaCatholic Univ Korea, Coll Med, St Vincents Hosp, Dept Family Med, Seoul, South Korea
Yoo, Byeong-Yeon
Kim, Dae-Hyun
论文数: 0引用数: 0
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Keimyung Univ, Dongsan Hosp, Dept Family Med, Daegu, South KoreaCatholic Univ Korea, Coll Med, St Vincents Hosp, Dept Family Med, Seoul, South Korea
Kim, Dae-Hyun
Lee, Sang-Hyun
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Ilsan Hosp, Natl Hlth Insurance Serv, Dept Family Med, Goyang, South KoreaCatholic Univ Korea, Coll Med, St Vincents Hosp, Dept Family Med, Seoul, South Korea
Lee, Sang-Hyun
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Park, Joo-Sung
Kim, Moon-Jong
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CHA Med Univ, CHA Bundang Med Ctr, Dept Family Med, Seongnam, South KoreaCatholic Univ Korea, Coll Med, St Vincents Hosp, Dept Family Med, Seoul, South Korea
Kim, Moon-Jong
Yoo, Jun-Hyun
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Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Family Med, Seoul, South KoreaCatholic Univ Korea, Coll Med, St Vincents Hosp, Dept Family Med, Seoul, South Korea
Yoo, Jun-Hyun
Cho, BeLong
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Seoul Natl Univ, Coll Med & Hosp, Dept Family Med, Seoul, South KoreaCatholic Univ Korea, Coll Med, St Vincents Hosp, Dept Family Med, Seoul, South Korea
Cho, BeLong
Kang, Hee-Cheol
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Yonsei Univ, Severance Hosp, Coll Med, Dept Family Med, Seoul, South KoreaCatholic Univ Korea, Coll Med, St Vincents Hosp, Dept Family Med, Seoul, South Korea
Kang, Hee-Cheol
Kim, Kwang-Min
论文数: 0引用数: 0
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Ajou Univ, Sch Med, Ajou Univ Hosp, Dept Family Med, Suwon, South KoreaCatholic Univ Korea, Coll Med, St Vincents Hosp, Dept Family Med, Seoul, South Korea
机构:
Pusan Natl Univ Hosp, Med Res Inst, Busan 602739, South Korea
Pusan Natl Univ Hosp, Clin Trial Ctr, Div Clin Pharmacol, Busan 602739, South KoreaPusan Natl Univ, Sch Med, Dept Urol, Busan 602739, South Korea
Choe, Sangmin
Park, Nam Cheol
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Pusan Natl Univ, Sch Med, Dept Urol, Busan 602739, South Korea
Pusan Natl Univ Hosp, Med Res Inst, Busan 602739, South KoreaPusan Natl Univ, Sch Med, Dept Urol, Busan 602739, South Korea
机构:
Medical Research Institute of Pusan National University Hospital
Division of Clinical Pharmacology, Clinical Trial Center, Pusan National University HospitalDepartment of Urology, Pusan National University School of Medicine
Sangmin Choe
Nam Cheol Park
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机构:
Department of Urology, Pusan National University School of Medicine
Medical Research Institute of Pusan National University HospitalDepartment of Urology, Pusan National University School of Medicine