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- [1] Rebastinib in combination with paclitaxel ablates TIE2-expressing macrophages, reduces metastasis, and increases survival in the PyMT metastatic breast cancer modelCANCER RESEARCH, 2013, 73Smith, B. D.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, Lawrence, KS USA Deciphera Pharmaceut LLC, Lawrence, KS USALeary, C. B.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, Lawrence, KS USA Deciphera Pharmaceut LLC, Lawrence, KS USAKaufman, M. D.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, Lawrence, KS USA Deciphera Pharmaceut LLC, Lawrence, KS USAHood, M. M.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, Lawrence, KS USA Deciphera Pharmaceut LLC, Lawrence, KS USALu, W-P论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, Lawrence, KS USA Deciphera Pharmaceut LLC, Lawrence, KS USATurner, B. A.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, Lawrence, KS USA Deciphera Pharmaceut LLC, Lawrence, KS USAVogeti, S.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, Lawrence, KS USA Deciphera Pharmaceut LLC, Lawrence, KS USAWise, S. C.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, Lawrence, KS USA Deciphera Pharmaceut LLC, Lawrence, KS USABerger, M. S.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, Lawrence, KS USA Deciphera Pharmaceut LLC, Lawrence, KS USAFlynn, D. L.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, Lawrence, KS USA Deciphera Pharmaceut LLC, Lawrence, KS USA
- [2] Rebastinib in combination with eribulin ablates TIE2-expressing macrophages, reduces metastasis, and increases survival in the PyMT metastatic breast cancer modelCANCER RESEARCH, 2013, 73Smith, B. D.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, Lawrence, KS USA Deciphera Pharmaceut LLC, Lawrence, KS USALeary, C. B.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, Lawrence, KS USA Deciphera Pharmaceut LLC, Lawrence, KS USAKaufman, M. D.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, Lawrence, KS USA Deciphera Pharmaceut LLC, Lawrence, KS USAHood, M. M.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, Lawrence, KS USA Deciphera Pharmaceut LLC, Lawrence, KS USALu, W-P论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, Lawrence, KS USA Deciphera Pharmaceut LLC, Lawrence, KS USATurner, B. A.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, Lawrence, KS USA Deciphera Pharmaceut LLC, Lawrence, KS USAVogeti, S.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, Lawrence, KS USA Deciphera Pharmaceut LLC, Lawrence, KS USAWise, S. C.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, Lawrence, KS USA Deciphera Pharmaceut LLC, Lawrence, KS USABerger, M. S.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, Lawrence, KS USA Deciphera Pharmaceut LLC, Lawrence, KS USAFlynn, D. L.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, Lawrence, KS USA Deciphera Pharmaceut LLC, Lawrence, KS USA
- [3] The Selective Tie2 Inhibitor Rebastinib Blocks Recruitment and Function of Tie2Hi Macrophages in Breast Cancer and Pancreatic Neuroendocrine TumorsMOLECULAR CANCER THERAPEUTICS, 2017, 16 (11) : 2486 - 2501Harney, Allison S.论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USA Albert Einstein Coll Med, Dept Radiol, New York, NY USA Albert Einstein Coll Med, Integrated Imaging Program, New York, NY USA Albert Einstein Coll Med, Gruss Lipper Biophoton Ctr, New York, NY USA Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USAKaragiannis, George S.论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USA Albert Einstein Coll Med, Integrated Imaging Program, New York, NY USA Albert Einstein Coll Med, Gruss Lipper Biophoton Ctr, New York, NY USA Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USAPignatelli, Jeanine论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USA Albert Einstein Coll Med, Gruss Lipper Biophoton Ctr, New York, NY USA Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USASmith, Bryan D.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, 500 Totten Pond Rd,6th Floor, Waltham, MA 02451 USA Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USAKadioglu, Ece论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USAWise, Scott C.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, 500 Totten Pond Rd,6th Floor, Waltham, MA 02451 USA Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USAHood, Molly M.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, 500 Totten Pond Rd,6th Floor, Waltham, MA 02451 USA Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USAKaufman, Michael D.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, 500 Totten Pond Rd,6th Floor, Waltham, MA 02451 USA Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USALeary, Cynthia B.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, 500 Totten Pond Rd,6th Floor, Waltham, MA 02451 USA Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USALu, Wei-Ping论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, 500 Totten Pond Rd,6th Floor, Waltham, MA 02451 USA Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USAAl-Ani, Gada论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, 500 Totten Pond Rd,6th Floor, Waltham, MA 02451 USA Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USAChen, Xiaoming论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USA Albert Einstein Coll Med, Gruss Lipper Biophoton Ctr, New York, NY USA Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USAEntenberg, David论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USA Albert Einstein Coll Med, Integrated Imaging Program, New York, NY USA Albert Einstein Coll Med, Gruss Lipper Biophoton Ctr, New York, NY USA Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USAOktay, Maja H.论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USA Albert Einstein Coll Med, Integrated Imaging Program, New York, NY USA Albert Einstein Coll Med, Dept Pathol, New York, NY USA Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USAWang, Yarong论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USA Albert Einstein Coll Med, Integrated Imaging Program, New York, NY USA Albert Einstein Coll Med, Gruss Lipper Biophoton Ctr, New York, NY USA Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USAChun, Lawrence论文数: 0 引用数: 0 h-index: 0机构: Emerald Bio, Bainbridge Isl, WA USA Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USADe Palma, Michele论文数: 0 引用数: 0 h-index: 0机构: Ecole Polytech Fed Lausanne, ISREC, CH-1015 Lausanne, Switzerland Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USAJones, Joan G.论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USA Albert Einstein Coll Med, Integrated Imaging Program, New York, NY USA Albert Einstein Coll Med, Dept Pathol, New York, NY USA Albert Einstein Coll Med, Dept Epidemiol Populat Hlth, New York, NY USA Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USAFlynn, Daniel L.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, 500 Totten Pond Rd,6th Floor, Waltham, MA 02451 USA Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USACondeelis, John S.论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USA Albert Einstein Coll Med, Integrated Imaging Program, New York, NY USA Albert Einstein Coll Med, Gruss Lipper Biophoton Ctr, New York, NY USA Albert Einstein Coll Med, Dept Anat & Struct Biol, New York, NY USA
- [4] The Tie2 antagonist rebastinib reduces ovarian cancer growth in a syngeneic murine modelBMC CANCER, 2025, 25 (01)Gupta, Vijayalaxmi G.论文数: 0 引用数: 0 h-index: 0机构: Washington Univ, Sch Med, Dept Obstet & Gynecol, 660 S Euclid Ave,Mailstop 8064-37-1005, St Louis, MO 63110 USA Washington Univ, Sch Med, Dept Obstet & Gynecol, 660 S Euclid Ave,Mailstop 8064-37-1005, St Louis, MO 63110 USARoby, Katherine F.论文数: 0 引用数: 0 h-index: 0机构: Univ Kansas, Med Ctr, Dept Cell Biol & Physiol, Kansas City, KS USA Washington Univ, Sch Med, Dept Obstet & Gynecol, 660 S Euclid Ave,Mailstop 8064-37-1005, St Louis, MO 63110 USAPathak, Harsh B.论文数: 0 引用数: 0 h-index: 0机构: Univ Kansas, Med Ctr, Dept Pathol, Kansas City, KS USA Washington Univ, Sch Med, Dept Obstet & Gynecol, 660 S Euclid Ave,Mailstop 8064-37-1005, St Louis, MO 63110 USAGodwin, Andrew K.论文数: 0 引用数: 0 h-index: 0机构: Univ Kansas, Med Ctr, Dept Pathol, Kansas City, KS USA Washington Univ, Sch Med, Dept Obstet & Gynecol, 660 S Euclid Ave,Mailstop 8064-37-1005, St Louis, MO 63110 USAGunewardena, Sumedha论文数: 0 引用数: 0 h-index: 0机构: Univ Kansas, Med Ctr, Dept Cell Biol & Physiol, Kansas City, KS USA Washington Univ, Sch Med, Dept Obstet & Gynecol, 660 S Euclid Ave,Mailstop 8064-37-1005, St Louis, MO 63110 USAKhabele, Dineo论文数: 0 引用数: 0 h-index: 0机构: Washington Univ, Sch Med, Dept Obstet & Gynecol, 660 S Euclid Ave,Mailstop 8064-37-1005, St Louis, MO 63110 USA Washington Univ, Sch Med, Dept Obstet & Gynecol, 660 S Euclid Ave,Mailstop 8064-37-1005, St Louis, MO 63110 USA
- [5] Rebastinib potently inhibits function of perivascular TIE2 expressing macrophages in vitro and in vivoCANCER RESEARCH, 2015, 75Harney, Allison论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Bronx, NY 10467 USA Albert Einstein Coll Med, Bronx, NY 10467 USAPignatelli, Jeanine论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Bronx, NY 10467 USA Albert Einstein Coll Med, Bronx, NY 10467 USALeung, Edison论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Bronx, NY 10467 USA Albert Einstein Coll Med, Bronx, NY 10467 USAOktay, Maja论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Bronx, NY 10467 USA Albert Einstein Coll Med, Bronx, NY 10467 USAWang, Yarong论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Bronx, NY 10467 USA Albert Einstein Coll Med, Bronx, NY 10467 USASmith, Bryan D.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, Cambridge, MA USA Albert Einstein Coll Med, Bronx, NY 10467 USAFlynn, Daniel L.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, Cambridge, MA USA Albert Einstein Coll Med, Bronx, NY 10467 USACondeelis, John S.论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Bronx, NY 10467 USA Albert Einstein Coll Med, Bronx, NY 10467 USA
- [6] Rebastinib, a small molecule TIE2 kinase inhibitor, prevents primary tumor growth and lung metastasis in the PyMT breast cancer modelCANCER RESEARCH, 2013, 73Smith, Bryan D.论文数: 0 引用数: 0 h-index: 0机构: Deciphena Pharmaceut LLC, Lawrence, KS USA Deciphena Pharmaceut LLC, Lawrence, KS USAHood, Molly M.论文数: 0 引用数: 0 h-index: 0机构: Deciphena Pharmaceut LLC, Lawrence, KS USA Deciphena Pharmaceut LLC, Lawrence, KS USAKaufman, Michael D.论文数: 0 引用数: 0 h-index: 0机构: Deciphena Pharmaceut LLC, Lawrence, KS USA Deciphena Pharmaceut LLC, Lawrence, KS USABerger, Mark论文数: 0 引用数: 0 h-index: 0机构: Deciphena Pharmaceut LLC, Lawrence, KS USA Deciphena Pharmaceut LLC, Lawrence, KS USAFlynn, Daniel L.论文数: 0 引用数: 0 h-index: 0机构: Deciphena Pharmaceut LLC, Lawrence, KS USA Deciphena Pharmaceut LLC, Lawrence, KS USAWise, Scott C.论文数: 0 引用数: 0 h-index: 0机构: Deciphena Pharmaceut LLC, Lawrence, KS USA Deciphena Pharmaceut LLC, Lawrence, KS USA
- [7] Rebastinib, a TIE2 antagonist improves chemotherapy response in homologous recombination proficient epithelial ovarian cancer murine modelsCANCER RESEARCH, 2022, 82 (12)Gupta, Vijayalaxmi G.论文数: 0 引用数: 0 h-index: 0机构: Washington Univ St Louis, St Louis, MO USA Washington Univ St Louis, St Louis, MO USARoby, Katherine F.论文数: 0 引用数: 0 h-index: 0机构: Univ Kansas, Med Ctr, Kansas City, KS 66103 USA Washington Univ St Louis, St Louis, MO USAPathak, Harsh B.论文数: 0 引用数: 0 h-index: 0机构: Univ Kansas, Med Ctr, Kansas City, KS 66103 USA Washington Univ St Louis, St Louis, MO USAGodwin, Andrew K.论文数: 0 引用数: 0 h-index: 0机构: Univ Kansas, Med Ctr, Kansas City, KS 66103 USA Washington Univ St Louis, St Louis, MO USAGunewardena, Sumedha论文数: 0 引用数: 0 h-index: 0机构: Univ Kansas, Med Ctr, Kansas City, KS 66103 USA Washington Univ St Louis, St Louis, MO USAKhabele, Dineo论文数: 0 引用数: 0 h-index: 0机构: Washington Univ St Louis, St Louis, MO USA Washington Univ St Louis, St Louis, MO USA
- [8] Experimental murine acute lung injury induces increase of pulmonary TIE2-expressing macrophagesJOURNAL OF INFLAMMATION-LONDON, 2018, 15Ehrentraut, Heidi论文数: 0 引用数: 0 h-index: 0机构: Univ Hosp Bonn, Dept Anesthesiol & Intens Care Med, Sigmund Freud Str 25, D-53127 Bonn, Germany Univ Hosp Bonn, Dept Anesthesiol & Intens Care Med, Sigmund Freud Str 25, D-53127 Bonn, GermanyWeisheit, Christina论文数: 0 引用数: 0 h-index: 0机构: Univ Hosp Bonn, Dept Anesthesiol & Intens Care Med, Sigmund Freud Str 25, D-53127 Bonn, Germany Univ Hosp Bonn, Dept Anesthesiol & Intens Care Med, Sigmund Freud Str 25, D-53127 Bonn, GermanyScheck, Marcel论文数: 0 引用数: 0 h-index: 0机构: Univ Hosp Bonn, Dept Anesthesiol & Intens Care Med, Sigmund Freud Str 25, D-53127 Bonn, Germany Univ Hosp Bonn, Dept Anesthesiol & Intens Care Med, Sigmund Freud Str 25, D-53127 Bonn, GermanyFrede, Stilla论文数: 0 引用数: 0 h-index: 0机构: Univ Hosp Bonn, Dept Anesthesiol & Intens Care Med, Sigmund Freud Str 25, D-53127 Bonn, Germany Univ Hosp Bonn, Dept Anesthesiol & Intens Care Med, Sigmund Freud Str 25, D-53127 Bonn, GermanyHilbert, Tobias论文数: 0 引用数: 0 h-index: 0机构: Univ Hosp Bonn, Dept Anesthesiol & Intens Care Med, Sigmund Freud Str 25, D-53127 Bonn, Germany Univ Hosp Bonn, Dept Anesthesiol & Intens Care Med, Sigmund Freud Str 25, D-53127 Bonn, Germany
- [9] Experimental murine acute lung injury induces increase of pulmonary TIE2-expressing macrophagesJournal of Inflammation, 15Heidi Ehrentraut论文数: 0 引用数: 0 h-index: 0机构: University Hospital Bonn,Department of Anesthesiology and Intensive Care MedicineChristina Weisheit论文数: 0 引用数: 0 h-index: 0机构: University Hospital Bonn,Department of Anesthesiology and Intensive Care MedicineMarcel Scheck论文数: 0 引用数: 0 h-index: 0机构: University Hospital Bonn,Department of Anesthesiology and Intensive Care MedicineStilla Frede论文数: 0 引用数: 0 h-index: 0机构: University Hospital Bonn,Department of Anesthesiology and Intensive Care MedicineTobias Hilbert论文数: 0 引用数: 0 h-index: 0机构: University Hospital Bonn,Department of Anesthesiology and Intensive Care Medicine
- [10] Phase Ib Clinical and Pharmacodynamic Study of the TIE2 Kinase Inhibitor Rebastinib with Paclitaxel or Eribulin in HER2-Negative Metastatic Breast CancerCLINICAL CANCER RESEARCH, 2025, 31 (02) : 266 - 277Anampa, Jesus D.论文数: 0 引用数: 0 h-index: 0机构: Montefiore Einstein Comprehens Canc Ctr, Dept Med Oncol, 1695 Eastchester Rd, Bronx, NY 10461 USA Montefiore Einstein Comprehens Canc Ctr, Dept Med Oncol, 1695 Eastchester Rd, Bronx, NY 10461 USAFlynn, Daniel L.论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, Waltham, MA USA Montefiore Einstein Comprehens Canc Ctr, Dept Med Oncol, 1695 Eastchester Rd, Bronx, NY 10461 USALeary, Cynthia论文数: 0 引用数: 0 h-index: 0机构: Deciphera Pharmaceut LLC, Waltham, MA USA Montefiore Einstein Comprehens Canc Ctr, Dept Med Oncol, 1695 Eastchester Rd, Bronx, NY 10461 USAOh, Sun论文数: 0 引用数: 0 h-index: 0机构: Montefiore Einstein Comprehens Canc Ctr, Dept Med Oncol, 1695 Eastchester Rd, Bronx, NY 10461 USA Montefiore Einstein Comprehens Canc Ctr, Dept Med Oncol, 1695 Eastchester Rd, Bronx, NY 10461 USAXue, Xiaonan论文数: 0 引用数: 0 h-index: 0机构: Albert Einstein Coll Med, Dept Epidemiol & Populat Hlth, Bronx, NY USA Montefiore Einstein Comprehens Canc Ctr, Dept Med Oncol, 1695 Eastchester Rd, Bronx, NY 10461 USAOktay, Maja H.论文数: 0 引用数: 0 h-index: 0机构: Montefiore Einstein Comprehens Canc Ctr, Tumor Microenvironm & Metastasis Program, Bronx, NY USA Montefiore Einstein Comprehens Canc Ctr, Dept Med Oncol, 1695 Eastchester Rd, Bronx, NY 10461 USACondeelis, John S.论文数: 0 引用数: 0 h-index: 0机构: Montefiore Einstein Comprehens Canc Ctr, Tumor Microenvironm & Metastasis Program, Bronx, NY USA Montefiore Einstein Comprehens Canc Ctr, Dept Med Oncol, 1695 Eastchester Rd, Bronx, NY 10461 USASparano, Joseph A.论文数: 0 引用数: 0 h-index: 0机构: Icahn Sch Med Mt Sinai, Tish Canc Inst, Div Hematol Oncol, New York, NY USA Montefiore Einstein Comprehens Canc Ctr, Dept Med Oncol, 1695 Eastchester Rd, Bronx, NY 10461 USA