Hymenamide F, new cyclic heptapeptide from marine sponge Hymeniacidon sp.

被引:41
|
作者
Kobayashi, J [1 ]
Nakamura, T [1 ]
Tsuda, M [1 ]
机构
[1] SANKYO CO LTD,ANALYT & METAB LABS,TOKYO 140,JAPAN
关键词
D O I
10.1016/0040-4020(96)00281-5
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A new cyclic heptapeptide, hymenamide F (1), was isolated from an Okinawan marine sponge Hymeniacidon sp. and the structure was elucidated on the basis of spectroscopic data of [Mso]-hymenamide F (2). The absolute configuration of each amino acid residue was determined by Marfey's method. The conformation in the solution of 2 is discussed on the basis of NMR data as well as molecular calculation. Copyright (C) 1996 Elsevier Science Ltd
引用
收藏
页码:6355 / 6360
页数:6
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