Soft tissue tumors of the head and neck region

被引:2
|
作者
Laffers, W. [1 ]
Stoehr, G. [1 ]
Goeke, F. [2 ]
Wardelmann, E. [3 ]
Keiner, S. [1 ]
Zipfel, M. [4 ]
Schueller, H. [5 ]
Gerstner, A. O. H. [1 ]
机构
[1] Univ Klinikum Bonn, Klin & Poliklin Hals Nasen Ohren Heilkunde Chirur, D-53105 Bonn, Germany
[2] Univ Klinikum Bonn, Inst Pathol, D-53105 Bonn, Germany
[3] Univ Klinikum Koln, Inst Pathol, Cologne, Germany
[4] Univ Klinikum Bonn, Innere Med Klin 3, D-53105 Bonn, Germany
[5] Univ Klinikum Bonn, Inst Radiol, Abt Strahlentherapie, D-53105 Bonn, Germany
关键词
Soft tissue neoplasm; Sarcoma; Multimodal treatment; Retrospective study; Adjuvant radiochemotherapy; PROGNOSTIC-FACTORS; CHILDHOOD-CANCER; SARCOMAS; ADULT; MANAGEMENT; CLASSIFICATION; METASTASIS; HIGHLIGHTS; RECURRENCE;
D O I
10.1007/s00106-013-2755-7
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
The incidence of soft tissue tumors of the head and neck region is low: 300 and 3 in 100,000 for benign and malignant tumors, respectively. However, sarcomas particularly show a wide variety of different histological subtypes. This article provides an overview of the soft tissue tumors of the head and neck region treated in the authors' institution. This is a retrospective study including 106 patients treated between 2002 and 2010 due to a soft tissue tumor. Tumor- and patient-specific data were collected (benign/malignant tumor, location, TNM classification, therapy, R classification, grade). In total, 77 benign tumors, 5 of intermediate benign/malignant nature and 24 sarcomas (with 7 different subtypes) were identified. Whereas the benign and intermediate tumors were treated by surgical removal, in 21 of the 24 sarcomas, treatment comprised a multimodal therapy regimen including radio- and/or chemotherapy. Whereas benign tumors can be successfully treated by surgical resection, there is no uniform therapy regimen for sarcomas due to the variety of different histological subtypes. Only case-specific interdisciplinary disease management can offer good perspectives for therapeutic success.
引用
收藏
页码:928 / 935
页数:8
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