Structural Analysis of Natural Products

被引：41

作者：

Prichystal, Jakub ^{[1
,2
]}

Schug, Kevin A. ^{[3
]}

Lemr, Karel ^{[1
,2
]}

Novak, Jiri ^{[1
]}

Havlicek, Vladimir ^{[1
,2
]}

机构：

[1] Acad Sci Czech Republ, Inst Microbiol, Videnska 1083, Prague 4, Czech Republic

[2] Palacky Univ, Dept Analyt Chem, Reg Ctr Adv Technol & Mat, 17 Listopadu 12, Olomouc 77146, Czech Republic

[3] Univ Texas Arlington, Dept Chem & Biochem, Arlington, TX 76019 USA

来源：

ANALYTICAL CHEMISTRY | 2016年 / 88卷 / 21期

关键词：

IONIZATION-MASS-SPECTROMETRY; BIOSYNTHETIC GENE CLUSTERS; NMR-SPECTROSCOPY; STRUCTURE ELUCIDATION; SABRE HYPERPOLARIZATION; IDENTIFICATION; RESOLUTION; DISCOVERY; METABOLITE; SPECTRA;

D O I：

10.1021/acs.analchem.6b02386

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Current mass spectrometry, nuclear magnetic resonance spectroscopy, and X-ray diffraction are presented as structure elucidation tools for analytical chemistry of natural products. Discovering new molecular entities combined with dereplication of known organic compounds represent prerequisites for biological assays and for respective applications as pharmaceuticals or molecular markers. Liquid chromatography is briefly addressed with respect to its use in mass spectrometry- and nuclear magnetic resonance-based metabolomics studies.

引用

页码：10338 / 10346

页数：9

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