Use of Nitric Oxide Producer L-Arginine during Infusion Therapy of Experimental Hemorrhagic Shock

被引：2

作者：

Grishina, G. V. ^{[1
]}

Gerbut, K. A. ^{[1
]}

Remizova, M. I. ^{[1
]}

Selivanov, E. A. ^{[1
]}

机构：

[1] Fed Med & Biol Agcy, Russian Res Inst Hematol & Transfusiol, Dept Blood Substitutes & Components, St Petersburg, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2013年 / 154卷 / 03期

关键词：

hemorrhagic shock; circulation; nitric oxide; L-arginine; RESUSCITATION;

D O I：

10.1007/s10517-013-1939-1

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Experiments on rats showed that infusion of NO precursor L-arginine before bleeding enhanced their tolerance to hemorrhagic shock. When infused after blood loss as a component of saline solution, L-arginine improved effi ciency of infusion therapy for hemorrhagic shock and increased survival rate of the animals.

引用

页码：312 / 315

页数：4

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