Vaccines against meningococcal diseases

被引:0
|
作者
Knuf, M. [1 ,2 ]
Vogel, U. [3 ]
机构
[1] Dr Horst Schmidt Klin Wiesbaden, Klin Kinder & Jugendliche, D-65199 Wiesbaden, Germany
[2] Univ Med Mainz, Mainz, Germany
[3] Univ Wurzburg, Inst Hyg & Mikrobiol, Wurzburg, Germany
关键词
Meningococcal infections; Neisseria meningitidis; Meningococcal vaccines; 4CMenB vaccine; Infants; BIVALENT RLP2086 VACCINE; CONJUGATE VACCINE; NEISSERIA-MENINGITIDIS; STRAIN COVERAGE; ROUTINE INFANT; GROUP-B; IMMUNOGENICITY; SAFETY; MULTICOMPONENT; VACCINATIONS;
D O I
10.1007/s00112-013-2920-9
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
In Germany vaccination with conjugated meningococcus C (MenC) vaccine is part of the national immunization program. Polysaccharide and conjugate vaccines against meningococci A, C, W-135 and Y are available and used according to the recommendations of the standing committee (STIKO). Since 2013 a new recombinant 4-component meningococcus B vaccine (4CMenB) has been approved. The strain coverage of this vaccine in Europe is approximately 80 %. Immunogenicity and safety data for various vaccine schedules were generated in several studies as well as for co-administration with routine vaccines which leads to higher fever rates. No recommendations from the STIKO are currently available for 4CMenB vaccines.
引用
收藏
页码:1146 / +
页数:7
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