Cancer Therapy and Osteoporosis: Approach to Evaluation and Management

被引：6

作者：

van Londen, G. J. ^{[2
,3
]}

Taxel, Pamela ^{[4
]}

Van Poznak, Catherine ^{[1
]}

机构：

[1] Univ Michigan, Ctr Comprehens Canc, Ann Arbor, MI 48109 USA

[2] Univ Pittsburgh, Sch Med, Div Geriatr, Dept Med, Pittsburgh, PA USA

[3] Univ Pittsburgh, Sch Med, Div Hematol Oncol, Pittsburgh, PA USA

[4] Univ Connecticut, Ctr Hlth, Div Endocrinol & Metab, Dept Med, Farmington, CT USA

来源：

SEMINARS IN ONCOLOGY | 2008年 / 35卷 / 06期

关键词：

D O I：

10.1053/j.seminoncol.2008.08.008

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The incidences of osteoporosis and cancer increase with age, and these two diagnoses are often made in the same individual. Both increasing age and hypogonadism associated with aging, as well as cancer therapies, can lead to loss of bone mass and increased risk for fragility fractures. Advancing age carries an association with increased incidence of cancers. Thus, cancer and its therapies may predispose an individual to osteoporosis and its associated morbidity and mortality. Prevention of bone loss and its consequent fractures is critical in the care of aging patients. This article reviews the mechanisms of bone metabolism and the principles of management of bone health in the older population with a history of cancer. © 2008 Elsevier Inc. All rights reserved.

引用

页码：643 / 651

页数：9

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