Concurrent urinary tract infection and stone disease: pathogenesis, diagnosis and management

被引:39
|
作者
Thomas, Ben [1 ]
Tolley, David [1 ]
机构
[1] Western Gen Hosp, Scottish Lithotripter Ctr, Edinburgh EH4 2XU, Midlothian, Scotland
来源
NATURE CLINICAL PRACTICE UROLOGY | 2008年 / 5卷 / 12期
关键词
kidney calculi; percutaneous nephrolithotomy; systemic sepsis; urinary tract infections;
D O I
10.1038/ncpuro1254
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Infection is implicated as the cause of stones in about 15% of stone formers, and the development of infection can complicate the management of pre-existing stones. Left untreated, both situations can result in loss of kidney function, and can, on occasion, be life threatening. The underlying pathophysiology of infection stones is generally well understood, but factors dictating why a particular individual should be affected are less clear, although obstruction is a uniformly recognized risk factor. Surgery is the mainstay of treatment for infection calculi: stone clearance is the goal and a range of minimally invasive treatments is available. Systemic sepsis remains the most serious complication of treatment, and, although rare, still occurs despite antibiotic prophylaxis. Once the stone and the causative infection have been removed, various strategies can be employed to minimize the risk of recurrence. When infection complicates pre-existing stone disease, the primary aim of management is to treat the infective episode and delay definitive stone management until the infection has cleared. In such cases where obstruction is also present, prompt drainage of the affected kidney is likely to prevent permanent renal damage, and may be life saving.
引用
收藏
页码:668 / 675
页数:8
相关论文
共 50 条
  • [1] Concurrent urinary tract infection and stone disease: pathogenesis, diagnosis and management
    Ben Thomas
    David Tolley
    Nature Clinical Practice Urology, 2008, 5 : 668 - 675
  • [2] Urinary tract stone in children: diagnosis and management
    Palinrungi, Muhammad Asykar
    INTERNATIONAL JOURNAL OF UROLOGY, 2020, 27 : 114 - 115
  • [3] IS URINARY-TRACT INFECTION CONCOMITANT WITH URINARY STONE DISEASE
    VASUDEVAN
    SACHIDEV, K
    SINDHU, S
    VATHSALA, R
    MARICKAR, YMF
    UROLOGICAL RESEARCH, 1988, 16 (03): : 202 - 202
  • [4] Urinary Tract Infections in Women: Pathogenesis, Diagnosis, and Management
    Matulay J.T.
    Mlynarczyk C.M.
    Cooper K.L.
    Current Bladder Dysfunction Reports, 2016, 11 (1) : 53 - 60
  • [5] Diagnosis and management of urinary tract infection in children
    Williams, Gabrielle J.
    Hodson, Elisabeth H.
    Isaacs, David
    Craig, Jonathan C.
    JOURNAL OF PAEDIATRICS AND CHILD HEALTH, 2012, 48 (04) : 296 - 301
  • [6] Diagnosis and management of urinary tract infection in pregnancy
    Berrington, AW
    Bint, AJ
    REVIEWS IN MEDICAL MICROBIOLOGY, 1999, 10 (01) : 27 - 36
  • [7] Diagnosis and Management of Urinary Tract Infection and Pyelonephritis
    Lane, David R.
    Takhar, Sukhjit S.
    EMERGENCY MEDICINE CLINICS OF NORTH AMERICA, 2011, 29 (03) : 539 - +
  • [8] Diagnosis and Management of Fungal Urinary Tract Infection
    Kauffman, Carol A.
    INFECTIOUS DISEASE CLINICS OF NORTH AMERICA, 2014, 28 (01) : 61 - +
  • [9] DIAGNOSIS AND MANAGEMENT OF URINARY-TRACT INFECTION
    MATTOO, TK
    ARCHIVES OF DISEASE IN CHILDHOOD, 1987, 62 (09) : 977 - 978
  • [10] Pathophysiology, diagnosis, and management of urinary tract infection in horses
    Frye, Melinda A.
    VETERINARY CLINICS OF NORTH AMERICA-EQUINE PRACTICE, 2006, 22 (02) : 497 - +