Delivery of a MalE CD4+-T-cell epitope into the major histocompatibility complex class II antigen presentation pathway by Bordetella pertussis adenylate cyclase

被引：0

作者：

Loucká, J

Schlecht, G

Vodolánová, J

Leclerc, C

Sebo, P

机构：

[1] CAS, Inst Microbiol, Lab Mol Biol Bacterial Pathogens, CZ-14220 Prague 4, Czech Republic

[2] Inst Pasteur, Unite Biol Regulat Immunitaires, F-75724 Paris, France

来源：

INFECTION AND IMMUNITY | 2002年 / 70卷 / 02期

关键词：

D O I：

暂无

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Recombinant adenylate cyclase toxoids are shown to deliver inserted foreign CD4(+)-T-cell epitopes into the major histocompatibility complex class II presentation pathway, inducing a specific CD4(+)-T-cell response in vivo and yielding in vitro stimulation of specific CD4(+) T cells at a 100-times-higher molar efficiency than the free peptide containing the epitope.

引用

页码：1002 / 1005

页数：4

共 50 条

[1] Delivery of CD8+ T-cell epitopes into major histocompatibility complex class I antigen presentation pathway by Bordetella pertussis adenylate cyclase:: Delineation of cell invasive structures and permissive insertion sites
Osicka, R
Osicková, A
Basar, T
Guermonprez, P
Rojas, M
Leclerc, C
Sebo, P
[J]. INFECTION AND IMMUNITY, 2000, 68 (01) : 247 - 256
[2] Direct delivery of the Bordetella pertussis adenylate cyclase toxin to the MHC class I antigen presentation pathway
Guermonprez, P
Ladant, D
Karimova, G
Ullmann, A
Leclerc, C
[J]. JOURNAL OF IMMUNOLOGY, 1999, 162 (04): : 1910 - 1916
[3] Megakaryocytes Direct CD4+T Cell Responses Via Major Histocompatibility Complex Class II Antigen Presentation
Camacho, Virginia
Guo, Karen
Hanc, Pavel
Carminita, Estelle
Becker, Isabelle C.
Harrington, Em
Italiano, Joseph E.
Machlus, Kellie R.
[J]. BLOOD, 2023, 142
[4] The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules
Watts, C
[J]. NATURE IMMUNOLOGY, 2004, 5 (07) : 685 - 692
[5] The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules
Colin Watts
[J]. Nature Immunology, 2004, 5 : 685 - 692
[6] DELIVERY OF PROTEIN ANTIGEN TO THE MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I-RESTRICTED ANTIGEN PRESENTATION PATHWAY
ZHOU, F
HUANG, L
[J]. JOURNAL OF DRUG TARGETING, 1995, 3 (02) : 91 - 109
[7] Intracellular delivery of a cytolytic T-lymphocyte epitope peptide by pertussis toxin to major histocompatibility complex class I without involvement of the cytosolic class I antigen processing pathway
Carbonetti, NH
Irish, TJ
Chen, CH
O'Connell, CB
Hadley, GA
McNamara, U
Tuskan, RG
Lewis, GK
[J]. INFECTION AND IMMUNITY, 1999, 67 (02) : 602 - 607
[8] Target HCVNS3CD4+ Th1 epitope to major histocompatibility complex class II pathway
Gao, M
Wang, HP
Wang, YN
Zhou, Y
Wang, QL
[J]. BIOTECHNOLOGY LETTERS, 2006, 28 (01) : 3 - 8
[9] Heat shock fusion proteins as vehicles for antigen delivery into the major histocompatibility complex class I presentation pathway
Suzue, K
Zhou, XZ
Eisen, HN
Young, RA
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (24) : 13146 - 13151
[10] CELL-INVASIVE ACTIVITY OF EPITOPE-TAGGED ADENYLATE-CYCLASE OF BORDETELLA-PERTUSSIS ALLOWS IN-VITRO PRESENTATION OF A FOREIGN EPITOPE TO CD8(+) CYTOTOXIC T-CELLS
SEBO, P
FAYOLLE, C
DANDRIA, O
LADANT, D
LECLERC, C
ULLMANN, A
[J]. INFECTION AND IMMUNITY, 1995, 63 (10) : 3851 - 3857

← 1 2 3 4 5 →