Short Communication Factors Influencing Time to CD4+ T Cell Counts >200 Cells/mm3 in HIV-Infected Individuals with CD4+ T Cell <50 Cells/mm3 at the Time of Starting Combination Antiretroviral Therapy

被引：0
|
作者：
Ku, Nam Su
Song, Young Goo
Han, Sang Hoon
Kim, Sun Bean
Kim, Hye-won
Jeong, Su Jin
Kim, Chang Oh
Kim, June Myung
Choi, Jun Yong [1 ]
机构：
[1] Yonsei Univ, Coll Med, Dept Internal Med, Seoul 120752, South Korea
来源：
AIDS RESEARCH AND HUMAN RETROVIRUSES | 2012年 / 28卷 / 12期
基金：
新加坡国家研究基金会;
关键词：
MEDICINE ASSOCIATION; DISEASES SOCIETY; VIRAL LOAD; VIRUS; DIAGNOSIS; AIDS; RECOMMENDATIONS; DETERMINANTS; TUBERCULOSIS; PROGRESSION;
D O I：
10.1089/aid.2011.0282
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We evaluated factors influencing time to CD4(+) T cell counts >200 cells/mm(3) in HIV-infected individuals with CD4(+) T cell <50 cells/mm(3) starting combination antiretroviral therapy (cART). We included a total of 29 patients on successful cART for more than 1 year. In a logistic regression model, higher pre-cART CD4(+) T cell counts were significantly associated with shorter time to CD4(+) T cell counts >200cells/mm(3) in HIV-infected individuals with baseline CD4(+) T cell <50 cells/mm(3). In survival analysis, patients having higher pre-cART CD4(+) T cell counts, especially 40-49 cells/mm(3), were at significantly higher risk of achieving CD4(+) T cell counts >200 cells/mm(3).
引用
收藏
页码：1594 / 1597
页数：4
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