Correlation of Survival Motor Neuron Expression in Leukocytes and Spinal Cord in Spinal Muscular Atrophy

被引：6
|
作者：
Tsai, Li-Kai [2 ]
Yang, Chih-Chao [2 ]
Ting, Chen-Hung [1 ]
Su, Yi-Ning [3 ,4 ]
Hwu, Wuh-Liang [3 ,4 ]
Li, Hung [1 ]
机构：
[1] Acad Sinica, Inst Mol Biol, Taipei 115, Taiwan
[2] Natl Taiwan Univ Hosp, Dept Neurol, Taipei, Taiwan
[3] Natl Taiwan Univ Hosp, Dept Med Genet, Taipei, Taiwan
[4] Natl Taiwan Univ, Coll Med, Taipei 10764, Taiwan
来源：
JOURNAL OF PEDIATRICS | 2009年 / 154卷 / 02期
关键词：
PERIPHERAL-BLOOD; MOUSE MODEL;
D O I：
10.1016/j.jpeds.2008.08.050
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Survival motor neuron (SMN) messenger RNA and protein levels in spinal muscular atrophy (SMA) model mice and in patients with SMA were measured. There was a high correlation between leukocyte and spinal cord SMN expression in SMA model mice and a moderate correlation between leukocyte SMN expression and age of disease onset in patients with SMA. (J Pediatr 2009;154:303-5)
引用
收藏
页码：303 / 305
页数：3
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