Internal use of n-butyl 2-cyanoacrylate (Indermil) for wound closure:: An experimental study

被引:25
|
作者
Pelissier, P [1 ]
Casoli, V
Le Bail, B
Martin, D
Baudet, J
机构
[1] Hop Pellegrin, Serv Chirurg Plast, F-33076 Bordeaux, France
[2] Hop Pellegrin, Lab Anatomopathol, F-33076 Bordeaux, France
关键词
D O I
10.1097/00006534-200111000-00034
中图分类号
R61 [外科手术学];
学科分类号
摘要
n-Butyl 2-cyanoacrylate glue (Indermil) was used for the Closure of dorsal wounds on rabbits. A 4-cm-long and 1-cm-wide laceration was created bilaterally on the back of 15 rabbits. One side was closed with absorbable 2-0 subcutaneous sutures and fast absorbable 3-0 skin sutures. whereas the other side was closed with cyanoacrylate glue applied on both deep and superficial tissues. A partial wound dehiscence occurred on the glue side in one animal at 2 weeks. The animal was killed at this time and considered a bad result in the glue group. In all other animals, no seroma, partial dehiscence, or wound infection occurred. Histopathologic analysis revealed that Indermil induced edema and a mild acute inflammatory reaction and resorbed almost completely within 2 months when applied to well-vascularized tissues. The application of glue on the cutaneous wound edges is a fast and Caw procedure that does not seem to delay or inhibit the healing process or its quality.
引用
收藏
页码:1661 / 1666
页数:6
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