The Preclinical and Clinical Activity of Poziotinib, a Potent, Selective Inhibitor of EGFR Exon 20 Mutant NSCLC

被引:3
|
作者
Elamin, Y. [1 ]
Robichaux, J. [1 ]
Lam, V. [2 ]
Tsao, A. [3 ]
Lu, C. [1 ]
Blumenschein, G. [4 ]
Kurie, J. [1 ]
Brahmer, J. [5 ]
Li, S.
Chen, T. [7 ]
Estrada-Bernal, A. [8 ]
Truini, A. [9 ]
Nilsson, M. [1 ]
Le, A.
Tan, Z. [1 ]
Zhang, S. [1 ]
Doebele, R. [10 ]
Politi, K. [9 ,12 ]
Yang, Z. [11 ]
Liu, S. [6 ]
Wong, K.
Heymach, J. [1 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Thorac Head & Neck Med Oncol, Houston, TX 77030 USA
[2] Univ Texas MD Anderson Canc Ctr, Dept Thorac Head & Neck Med Oncol, Houston, TX 77030 USA
[3] Univ Texas MD Anderson Canc Ctr, Thorac & Head & Neck Med Oncol, Houston, TX 77030 USA
[4] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA
[5] Johns Hopkins, Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD USA
[6] Dana Farber Canc Inst, Med Oncol, Boston, MA 02115 USA
[7] Dana Farber Canc Inst, Boston, MA 02115 USA
[8] Univ Colorado Amc, Med Oncol, Aurora, CO USA
[9] Yale Univ, Pathol, New Haven, CT USA
[10] Univ Colorado, Div Med Oncol, Aurora, CO USA
[11] Spectrum Pharmaceut, Irvine, CA USA
[12] NYU, Langone Med Ctr, Div Hematol Oncol, New York, NY USA
关键词
EGFR Exon 20 Insertion mutation; Novel targeted therapy;
D O I
10.1016/j.jtho.2017.09.394
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
OA 12.01
引用
收藏
页码:S1776 / S1776
页数:1
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