Pulmonary Hypertension after Hematopoietic Stem Cell Transplantation

被引：63
|
作者：
Dandoy, Christopher E. [1 ]
Hirsch, Russel [2 ]
Chima, Ranjit [3 ]
Davies, Stella M. [1 ]
Jodele, Sonata [1 ]
机构：
[1] Cincinnati Childrens Hosp Med Ctr, Div Bone Marrow Transplant & Immune Deficiency, Cincinnati, OH 45229 USA
[2] Cincinnati Childrens Hosp Med Ctr, Div Cardiol, Cincinnati, OH 45229 USA
[3] Cincinnati Childrens Hosp Med Ctr, Div Crit Care Med, Cincinnati, OH 45229 USA
来源：
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION | 2013年 / 19卷 / 11期
关键词：
Pulmonary hypertension; Pulmonary arterial hypertension; Pulmonary veno-occlusive disease; Thrombotic microangiopathy; BONE-MARROW-TRANSPLANTATION; VENOOCCLUSIVE DISEASE; ARTERIAL-HYPERTENSION; COMPUTED-TOMOGRAPHY; PEDIATRIC-PATIENTS; COMPLICATIONS; PATHOPHYSIOLOGY; VASCULOPATHY; THERAPY; PATIENT;
D O I：
10.1016/j.bbmt.2013.07.017
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Pulmonary hypertension (PH) is a potentially fatal complication of hematopoietic stem cell transplantation (HSCT). Given its nonspecific clinical presentation, it is likely that this clinical entity is underdiagnosed after HSCT. Data describing the incidence, risk factors, and etiology of PH in HSCT recipients are minimal. Physicians caring for HSCT recipients should be aware of this severe post-transplant complication because timely diagnosis and treatment may allow improved clinical outcomes. We summarize the pathophysiology, clinical presentation, diagnosis, and management of PH in HSCT recipients. (C) 2013 American Society for Blood and Marrow Transplantation.
引用
收藏
页码：1546 / 1556
页数：11
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