Circulating and exhaled vascular endothelial growth factor in asthmatic pregnancy

被引：10

作者：

Bikov, Andras ^{[1
]}

Bohacs, Aniko ^{[1
]}

Eszes, Noemi ^{[1
]}

Weiszhar, Zsoka ^{[1
]}

Ivancso, Istvan ^{[1
]}

Muller, Veronika ^{[1
]}

Rigo, Janos, Jr. ^{[2
]}

Losonczy, Gyorgy ^{[1
]}

Tamasi, Lilla ^{[1
]}

Horvath, Ildiko ^{[1
]}

机构：

[1] Semmelweis Univ, Dept Pulmonol, H-1125 Budapest, Hungary

[2] Semmelweis Univ, Dept Obstet & Gynecol 1, H-1125 Budapest, Hungary

来源：

BIOMARKERS | 2012年 / 17卷 / 07期

基金：

匈牙利科学研究基金会;

关键词：

Asthma; breath test; pregnancy; vascular endothelial growth factor; BREATH CONDENSATE; INDUCED SPUTUM; PLASMA; SERUM; VEGF; ANGIOGENESIS; INVOLVEMENT; EXPRESSION; RECEPTORS; SFLT1;

D O I：

10.3109/1354750X.2012.713004

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Context: Vascular endothelial growth factor (VEGF) plays a role in asthma and pathological pregnancies. Objective: This is the first study assessing plasma and exhaled breath condensate VEGF levels in asthmatic pregnancy. Material and methods: Thirty-one asthmatic pregnant, 29 asthmatic nonpregnant, 28 healthy pregnant and 22 healthy nonpregnant women were enrolled. Plasma was collected in all subjects, EBC in 57 volunteers for VEGF measurements. Results: Plasma VEGF decreased in both pregnant groups (p < 0.01), without any differences between the asthmatic and the respective nonasthmatic groups (p > 0.05). VEGF was undetectable in EBC. Conclusion: Concomitant asthma does not affect plasma VEGF during pregnancy.

引用

页码：648 / 654

页数：7

共 50 条

[1] Circulating and exhaled vascular endothelial growth factor in asthmatic pregnancy
Bikov, Andras
Bohacs, Aniko
Eszes, Noemi
Weiszhar, Zsoka
Ivancso, Istvan
Muller, Veronika
Rigo, Janos
Losonczy, Gyorgy
Tamasi, Lilla
Horvath, Ildiko
[J]. EUROPEAN RESPIRATORY JOURNAL, 2013, 42
[2] Circulating vascular permeability factor vascular endothelial growth factor in erythroderma
Creamer, D
Allen, MH
Groves, RW
Barker, JNWN
[J]. LANCET, 1996, 348 (9034): : 1101 - 1101
[3] Circulating levels of nitric oxide and vascular endothelial growth factor throughout ovine pregnancy
Vonnahme, KA
Wilson, ME
Li, Y
Rupnow, HL
Phernetton, TM
Ford, SP
Magness, RR
[J]. JOURNAL OF PHYSIOLOGY-LONDON, 2005, 565 (01): : 101 - 109
[4] Pitfalls in the measurement of circulating vascular endothelial growth factor
Jelkmann, W
[J]. CLINICAL CHEMISTRY, 2001, 47 (04) : 617 - 623
[5] Maternal circulating vascular endothelial growth factor (VEGF) is elevated in high altitude pregnancy.
Zamudio, S
Wheeler, T
Moore, LG
[J]. AMERICAN JOURNAL OF HUMAN BIOLOGY, 2002, 14 (01) : 139 - 139
[6] Preeclampsia: The endothelium, circulating factor(s) and vascular endothelial growth factor
Hayman, R
Brockelsby, J
Kenny, L
Baker, P
[J]. JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION, 1999, 6 (01) : 3 - 10
[7] Preeclampsia: The Endothelium, Circulating Factor(s) and Vascular Endothelial Growth Factor
Richard Hayman
Jeremy Brockelsby
Louise Kenny
Philip Baker
[J]. The Journal of the Society for Gynecologic Investigation: JSGI, 1999, 6 (1): : 3 - 10
[8] Vascular Endothelial Growth Factor as a Key Inducer of Angiogenesis in the Asthmatic Airways
Meyer, Norbert
Akdis, Cezmi A.
[J]. CURRENT ALLERGY AND ASTHMA REPORTS, 2013, 13 (01) : 1 - 9
[9] Vascular Endothelial Growth Factor as a Key Inducer of Angiogenesis in the Asthmatic Airways
Norbert Meyer
Cezmi A. Akdis
[J]. Current Allergy and Asthma Reports, 2013, 13 : 1 - 9
[10] Vascular endothelial growth factor gene polymorphisms and pregnancy
Galazios, George
Papazoglou, Dimitrios
Tsikouras, Panagiotis
Kolios, George
[J]. JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, 2009, 22 (05): : 371 - 378

← 1 2 3 4 5 →