Pitfalls in Proteomics: Avoiding Problems That Can Occur Before Data Acquisition Begins

被引：0

作者：

Meston, Daniel ^{[1
]}

Stoll, Dwight R. ^{[2
]}

机构：

[1] Free Univ Brussels, Brussels, Belgium

[2] Gustavus Adolphus Coll, Chem, St Peter, MN 56082 USA

来源：

LCGC NORTH AMERICA | 2022年 / 40卷 / 11期

关键词：

COVID-19 SHUTDOWN TIPS; TRICKS;

D O I：

暂无

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The analysis of peptides using liquid chromatography-mass spectrometry (LC-MS) for proteomics applications is powerful and can yield tremendously rich data sets. However, the exquisite sensitivity and global applicability of MS detection also makes it prone to contaminants that can easily and seriously compromise the quality of a data set. A short list of tips and tricks can increase the likelihood of consistently producing good LC-MS data in this context and streamline the troubleshooting process when problems do eventually occur.

引用

页码：524 / 528

页数：5

共 9 条

[1] Pitfalls in Poteomics: Avoiding Problems That Can Occur Before Data Acquisition Begins
Meston, Daniel
Stoll, Dwight R.
[J]. LCGC EUROPE, 2022, 35 (10) : 450 - 453
[2] FMEA can head off potential problems before they occur
Yasenchak, LP
[J]. MODERN PLASTICS, 2000, 77 (05): : 80 - 80
[3] Avoiding pitfalls: Bayes factors can be a reliable tool for post hoc data selection in implicit learning
M. Leganes-Fonteneau
R. Scott
T. Duka
Z. Dienes
[J]. Psychonomic Bulletin & Review, 2021, 28 : 1848 - 1859
[4] Avoiding pitfalls: Bayes factors can be a reliable tool for post hoc data selection in implicit learning
Leganes-Fonteneau, M.
Scott, R.
Duka, T.
Dienes, Z.
[J]. PSYCHONOMIC BULLETIN & REVIEW, 2021, 28 (06) : 1848 - 1859
[5] Can animal data predict human outcome? Problems and pitfalls of translational animal research
Martic-Kehl, Marianne I.
Schibli, Roger
Schubiger, P. August
[J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2012, 39 (09) : 1492 - 1496
[6] Can animal data predict human outcome? Problems and pitfalls of translational animal research
Marianne I. Martić-Kehl
Roger Schibli
P. August Schubiger
[J]. European Journal of Nuclear Medicine and Molecular Imaging, 2012, 39 : 1492 - 1496
[7] ACQUISITION OF ENDOGENOUS ECOTROPIC MULV CAN OCCUR BEFORE THE LATE ONE-CELL STAGE IN THE GENITAL-TRACT OF SWR/J-RF/J HYBRID FEMALES
RICHOUX, V
PANTHIER, JJ
SALMON, AM
CONDAMINE, H
[J]. JOURNAL OF EXPERIMENTAL ZOOLOGY, 1989, 252 (01): : 96 - 100
[8] Improving single cell proteomics experiments: how can we best utilize latest-generation data acquisition and MS instrument architecture?
Matzinger, Manuel
Mechtler, Karl
[J]. EXPERT REVIEW OF PROTEOMICS, 2023, 20 (10) : 193 - 195
[9] Subtle Differences During Posturography Testing Can Influence Postural Sway Results: The Effects of Talking, Time Before Data Acquisition, and Visual Fixation
Taylor, Melissa R.
Sutton, Erin E.
Diestelkamp, Wiebke S.
Bigelow, Kimberly Edginton
[J]. JOURNAL OF APPLIED BIOMECHANICS, 2015, 31 (05) : 324 - 329

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