Two new iridoid glycosides from the leaves of Callicarpa nudiflora

被引：22

作者：

Wang, Jie ^{[1
,2
]}

Fu, Hui-Zheng ^{[1
]}

Luo, Yue-Hua ^{[1
]}

Ma, Yuan-Yu ^{[1
,2
]}

Huang, Bo ^{[1
]}

Ma, Shuang-Cheng ^{[3
]}

机构：

[1] Jiangxi Prov Inst Drug Control, Jiangxi Prov Engn Res Ctr Drug & Med Device Qual, Nanchang 330029, Jiangxi, Peoples R China

[2] Nanchang Univ, Coll Pharm, Pharmaceut Dept, Nanchang 330006, Jiangxi, Peoples R China

[3] Natl Inst Food & Drug Control, Res & Inspect Ctr Tradit Chinese Med & Ethnomed, Beijing 100050, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2018年 / 20卷 / 03期

基金：

中国国家自然科学基金;

关键词：

Verbenacase; Callicarpa nudiflora; iridoid glycosides; hepatoprotective activity; CHEMICAL-CONSTITUENTS; GLUCOSIDES;

D O I：

10.1080/10286020.2017.1323884

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new iridoid glycosides, callicoside C (1) and callicoside D (2), together with three known compounds (3-5), were isolated from the leaves of Callicarpa nudiflora. Their structures were established by 1D and 2D NMR spectroscopy and mass spectrometry. In an in vitro bioassay, compound 1 showed pronounced hepatoprotective activity against d-galactosamine-induced toxicity in WB-F344 rat hepatic epithelial stem-like cells. [GRAPHICS] .

引用

页码：242 / 248

页数：7

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