Improved nonviral gene transfer and transgene expression by using the minimalistic MIDGE-vector system

被引:0
|
作者
Kobelt, D. [1 ]
Stein, Ulrike [1 ]
Schmidt, Manuel [1 ]
Aumann, Jutta [1 ]
Schlag, Peter M. [1 ]
Walther, Wolfgang [1 ]
机构
[1] MDC Berlin Buch, Berlin, Germany
关键词
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
329
引用
收藏
页码:139 / 139
页数:1
相关论文
共 50 条
  • [1] Improved transfer efficiency and transgene expression in vitro and in vivo using the minimalistic nonviral MIDGE expression system
    Walther, Wolfgang
    Kobelt, Dennis
    Aumann, Jutta
    Schlag, Peter
    [J]. CANCER RESEARCH, 2009, 69
  • [2] Use of the minimalistic nonviral MIDGE expression system for improved in vitro and in vivo transfer
    Walther, W.
    Kobelt, D.
    Aumann, J.
    Fichtner, I.
    Schmidt, M.
    Schlag, P. M.
    [J]. HUMAN GENE THERAPY, 2010, 21 (10) : 1408 - 1408
  • [3] Employment of the minimalistic MIDGE vector for improved nonviral cancer gene therapy
    Kobelt, D.
    Schmidt, M.
    Aumann, J.
    Fichtner, I.
    Schlag, P. M.
    Walther, W.
    [J]. ONKOLOGIE, 2010, 33 : 152 - 152
  • [4] Nonviral MIDGE-vector based TNF-alpha gene transfer for in vitro and in vivo chemosensitization of malignant melanoma
    Kobelt, D.
    Aumann, J.
    Schmidt, M.
    Schroff, M.
    Fichtner, I.
    Schlag, P. M.
    Walther, W.
    [J]. HUMAN GENE THERAPY, 2011, 22 (10) : A89 - A89
  • [5] Chemosensitization of melanoma by use of the minimalistic nonviral MIDGE expression system for improved TNF-alpha expression in vitro and in vivo
    Walther, Wolfgang
    Kobelt, Dennis
    Aumann, Jutta
    Fichtner, Iduna
    Schmidt, Manuel
    Schlag, Peter M.
    [J]. CANCER RESEARCH, 2011, 71
  • [6] First results of a phase I gene therapy trial for nonviral jet-injection gene transfer of the TNF-alpha expressing minimalistic MIDGE vector in melanoma patients
    Kiecker, F.
    Kobelt, D.
    Chiola, F. P.
    Aumann, J.
    Schmidt, M.
    Roewert-Huber, H. -J.
    Schlag, P. M.
    Walther, W.
    [J]. JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2014, 12 : 36 - 37
  • [7] Phase I gene therapy trial for nonviral jet-injection gene transfer of the TNF-alpha expressing minimalistic MIDGE vector (MGN1404) in melanoma patients
    Walther, W.
    Kobelt, D.
    Pahle, J.
    Aumann, J.
    Schmidt, M.
    Schlag, P. M.
    Roewert-Huber, H. -J.
    Kiecker, F.
    [J]. ONCOLOGY RESEARCH AND TREATMENT, 2016, 39 : 39 - 39
  • [8] Polyfection as nonviral gene transfer method -: Design of novel nonviral vector using α-cyclodextrin
    Arima, H
    [J]. YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 2004, 124 (07): : 451 - 464
  • [9] Reduction-sensitive lipopolyamines as a novel nonviral gene delivery system for modulated release of DNA with improved transgene expression
    Byk, G
    Wetzer, B
    Frederic, M
    Dubertret, C
    Pitard, B
    Jaslin, G
    Scherman, D
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2000, 43 (23) : 4377 - 4387
  • [10] Phase I nonviral gene therapy trial: jet-injection gene transfers of the TNF-alpha expressing minimalistic MIDGE vector in patients with malignant melanoma
    Kiecker, F.
    Kobelt, D.
    Pahle, J.
    Schmidt, M.
    Schlag, P.
    Walther, W.
    [J]. JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2016, 14 : 14 - 14