In vitro activity of telavancin against resistant gram-positive bacteria

被引：76
|
作者：
Krause, Kevin M. [1 ]
Renelli, Marika [1 ]
Difuntorum, Stacey [1 ]
Wu, Terry X. [1 ]
Debabov, Dmitri V. [1 ]
Benton, Bret M. [1 ]
机构：
[1] Theravance Inc, San Francisco, CA 94080 USA
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2008年 / 52卷 / 07期
关键词：
D O I：
10.1128/AAC.01398-07
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The in vitro activity of telavancin was tested against 743 predominantly antimicrobial-resistant, gram-positive isolates. Telavancin was highly active against methicillin-resistant staphylococci (MIC90, 0.5 to 1 mu g/ml), streptococci (all MICs, <= 0.12 mu g/ml), and VanB-type enterococci (all MICs, <= 2 mu g/ml). Time-kill studies demonstrated the potent bactericidal activity of telavancin.
引用
下载
收藏
页码：2647 / 2652
页数：6
相关论文
共 50 条
  • [1] In vitro activity of levofloxacin against gram-positive bacteria
    Montanari, MP
    Mingoia, M
    Marchetti, F
    Varaldo, PE
    CHEMOTHERAPY, 1999, 45 (06) : 411 - 417
  • [2] In vitro activity of telavancin and comparators against selected groups of Gram-positive cocci
    Hope, Russell
    Chaudhry, Aiysha
    Adkin, Rachael
    Livermore, David M.
    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2013, 41 (03) : 213 - 217
  • [3] In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe
    Jansen, W. T. A.
    Verel, A.
    Verhoef, J.
    Milatovic, D.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2007, 51 (09) : 3420 - 3424
  • [4] Activity of newer fluoroquinolones in vitro against gram-positive bacteria
    Eliopoulos, GM
    DRUGS, 1999, 58 (Suppl 2) : 23 - 28
  • [5] Activity of Newer Fluoroquinolones In Vitro Against Gram-Positive Bacteria
    George M. Eliopoulos
    Drugs, 1999, 58 : 23 - 28
  • [6] IN VITRO ACTIVITY OF LINEZOLID/ERTAPENEM COMBINATION IN RESISTANT GRAM-POSITIVE BACTERIA
    Erac, Bayri
    Tasli, Hueseyin
    Ermertcan, Safak
    Cilli, Feriha
    Limoncu, Mine Hosgoer
    MIKROBIYOLOJI BULTENI, 2009, 43 (01): : 45 - 51
  • [7] ACTIVITY OF GLYCOPEPTIDES AGAINST VANCOMYCIN-RESISTANT GRAM-POSITIVE BACTERIA
    NICAS, TI
    COLE, CT
    PRESTON, DA
    SCHABEL, AA
    NAGARAJAN, R
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1989, 33 (09) : 1477 - 1481
  • [8] Comparative in vitro-activities of telavancin and other antibacterial agents against selected gram-positive bacteria
    Brauers, J.
    Bagel, S.
    Kresken, M.
    INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2006, 296 : 111 - 111
  • [9] Telavancin activity in vitro tested against a worldwide collection of Gram-positive clinical isolates (2014)
    Duncan, Leonard R.
    Sader, Helio S.
    Smart, Jennifer I.
    Flamm, Robert K.
    Mendes, Rodrigo E.
    JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE, 2017, 10 : 271 - 276
  • [10] In vitro activity of LY 333328 against anaerobic Gram-positive bacteria
    Sillerström, E
    Wahlund, E
    Nord, CE
    JOURNAL OF CHEMOTHERAPY, 1999, 11 (02) : 90 - 92
12345