Inhibition of tyrosinase activity on dopamine hydrochloride by kojic acid

被引：0
|
作者：
Sariri, R [1 ]
Moghimi, R [1 ]
Ranjbar, RB [1 ]
机构：
[1] Gilan Univ, Dept Biol, Rasht, Iran
来源：
ASIAN JOURNAL OF CHEMISTRY | 2006年 / 18卷 / 01期
关键词：
tyrosinase; enzyme kinetics; enzyme inhibition; polyphenol oxidase; kojic acid;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The inhibition effect of kojic acid on tyrosinase activity was studied and the rate of enzymatic reaction in presence and absence of the inhibitor was calculated. It was shown that increasing the concentration of inhibitors reduces the enzymatic reaction rate linearly. The kinetics of inhibition by kojic acid was studied and the Michaelis constants calculated. It was found that kojic acid could non-competitively inhibit the tyrosinase action on its substrate, dopamine hydrochlodride under specified conditions.
引用
收藏
页码：15 / 19
页数：5
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