Zinc Hydride-Catalyzed Hydrofuntionalization of Ketones

被引：40

作者：

Sahoo, Rajata Kumar ^{[1
]}

Mahato, Mamata ^{[1
]}

Jana, Achintya ^{[2
]}

Nembenna, Sharanappa ^{[1
]}

机构：

[1] Homi Bhabha Natl Inst HBNI, Natl Inst Sci Educ & Res NISER, Sch Chem Sci, Bhubaneswar 752050, Odisha, India

[2] Indian Inst Sci, Undergrad Programme, Bangalore 560012, Karnataka, India

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2020年 / 85卷 / 17期

关键词：

N-HETEROCYCLIC CARBENE; COMPLEXES SYNTHESIS; HYDROSILYLATION; HYDROBORATION; ALDEHYDES; REACTIVITY; REDUCTION; ALKYNES; IMINES;

D O I：

10.1021/acs.joc.0c01285

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three new dimeric bis-guanidinate zinc(II) alkyl, halide, and hydride complexes [LZnEt](2) (1), [LZnI](2) (2) and [LZnH](2) (3) were prepared. Compound 3 was successfully employed for the hydrosilylation and hydroboration of a vast number of ketones. The catalytic performance of 3 in the hydroboration of acetophenone exhibits a turnover frequency, reaching up to 5800 h(-)(1), outperforming that of reported zinc hydride catalysts. Notably, both intra- and intermolecular chemoselective hydrosilylation and hydroboration reactions have been investigated.

引用

页码：11200 / 11210

页数：11

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