Persistent Globe Flattening in Astronauts following Long-Duration Spaceflight

被引：22

作者：

Mader, Thomas H. ^{[1
]}

Gibson, C. Robert ^{[2
,3
]}

Barratt, Michael R. ^{[4
]}

Miller, Neil R. ^{[5
]}

Subramanian, Prem S. ^{[6
]}

Killer, Hanspeter E. ^{[7
]}

Tarver, William J. ^{[8
]}

Sargsyan, Ashot E. ^{[3
]}

Garcia, Kathleen ^{[3
]}

Hart, Stephen F. ^{[8
]}

Kramer, Larry A. ^{[9
]}

Riascos, Roy ^{[9
]}

Brunstetter, Tyson J. ^{[4
]}

Lipsky, William ^{[2
]}

Wostyn, Peter ^{[10
]}

Lee, Andrew G. ^{[11
,12
,13
,14
,15
,16
,17
,18
,19
]}

机构：

[1] US Army, COL R, 3509 Red Rock Dr, Moab, UT 84532 USA

[2] Coastal Eye Associates, Webster, TX USA

[3] KBR, Houston, TX USA

[4] NASA, Johnson Space Ctr, Houston, TX USA

[5] Johns Hopkins Univ Hosp, Wilmer Eye Inst, Baltimore, MD 21287 USA

[6] Univ Colorado, Sch Med, Sue Anschutz Rodgers UCHlth Eye Ctr, Dept Ophthalmol, Aurora, CO USA

[7] Kantonsspital Aarau, Dept Ophthalmol, Aarau, Switzerland

[8] NASA, Johnson Space Ctr, Space Med, Houston, TX USA

[9] Univ Texas Hlth Sci Ctr Houston, Dept Diagnost Imaging & Intervent, Houston, TX 77030 USA

[10] PC Sint Amandus, Dept Psychiat, Beernem, Belgium

[11] Houston Methodist Hosp, Blanton Eye Inst, Dept Ophthalmol, Houston, TX 77030 USA

[12] Univ Iowa Hosp & Clin, Dept Ophthalmol, Iowa City, IA 52242 USA

[13] Weill Cornell Med, Dept Ophthalmol, New York, NY USA

[14] Weill Cornell Med, Dept Neurol, New York, NY USA

[15] Weill Cornell Med, Dept Neurosurg, New York, NY USA

[16] Univ Texas Med Branch, Dept Ophthalmol, Galveston, TX 77555 USA

[17] Baylor Coll Med, Dept Ophthalmol, Houston, TX 77030 USA

[18] Univ Texas MD Anderson Canc Ctr, Dept Ophthalmol, Houston, TX 77030 USA

[19] Texas A&M Coll Med, Dept Ophthalmol, Bryan, TX USA

来源：

NEURO-OPHTHALMOLOGY | 2021年 / 45卷 / 01期

关键词：

SANS; astronaut; international space station (ISS); visual changes; hyperopic shift; long-duration space flight (LDSF); OPTIC DISC EDEMA; VISUAL IMPAIRMENT; MICROGRAVITY;

D O I：

10.1080/01658107.2020.1791189

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Posterior globe flattening has been well-documented in astronauts both during and after long-duration space flight (LDSF) and has been observed as early as 10 days into a mission on the International Space Station. Globe flattening (GF) is thought to be caused by the disc centred anterior forces created by elevated volume and/or pressure within the optic nerve sheath (ONS). This might be the result of increased intracranial pressure, increased intraorbital ONS pressure from compartmentalisation or a combination of these mechanisms. We report posterior GF in three astronauts that has persisted for 7 years or more following their return from LDSFs suggesting that permanent scleral remodelling may have occurred.

引用

页码：29 / 35

页数：7

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