Gold-catalyzed synthesis of substituted 2-aminofurans via formal [4+1]-cycloadditions on 3-en-1-ynamides

被引：137
|
作者：
Dateer, Ramesh B. [1 ]
Pati, Kamalkishore [1 ]
Liu, Rai-Shung [1 ]
机构：
[1] Natl Tsing Hua Univ, Dept Chem, Hsinchu, Taiwan
来源：
CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 57期
关键词：
ALPHA; BETA-UNSATURATED CARBONYL-COMPOUNDS; ASYMMETRIC 4+1 CYCLOADDITION; AZA-NAZAROV REACTION; BOND FORMATION; METAL; MONOXIDE; YNAMIDES; ACCESS; FURANS; ISOCYANIDES;
D O I：
10.1039/c2cc33030j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Gold-catalyzed formal [4+1]-cycloadditions between 3-en-1-ynamides 1 and 8-methylquinoline oxide are reported. The success of this reaction relies on a hypothetic oxa-Nazarov cyclization on gold-stabilized allylic cations. Preliminary results on a new 1,2-difunctionalization of 3-en-1-ynamide are also reported.
引用
收藏
页码：7200 / 7202
页数：3
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