Thrombopoietin (TPO) Receptor Agonist Eltrombopag in Combination with Azacitidine (AZA) for Primary Treatment of Myelodysplastic Syndromes (MDS) Patients with Thrombocytopenia: Outcomes from the Randomized, Placebo-Controlled, Phase III Support Study

被引：6

作者：

Dickinson, Michael J. ^{[1
]}

Cherif, Honor ^{[2
]}

Fenaux, Pierre ^{[3
]}

Mittleman, Moshe ^{[4
]}

Verma, Amit ^{[5
]}

Portella, Maria Socorro O. ^{[6
]}

Burgess, Paul ^{[7
]}

Platzbecker, Uwe ^{[8
]}

机构：

[1] Peter MacCallum Canc Ctr, Div Canc Med, Melbourne, Australia

[2] Univ Uppsala Hosp, Dept Med Sci, Uppsala, Sweden

[3] Univ Paris XIII, Hop Avicenne, AP HP, Bobigny, France

[4] Tel Aviv Univ, Tel Aviv Sourasky Med Ctr, Tel Aviv, Israel

[5] Einstein Montefiore Canc Ctr, Bronx, NY USA

[6] Novartis Pharmaceutical Corp, E Hanover, NJ USA

[7] Novartis Pharma AG, Basel, Switzerland

[8] Tech Univ Dresden, Carl Gustav Carus, Univ Klinikum, Dresden, Germany

来源：

BLOOD | 2016年 / 128卷 / 22期

关键词：

D O I：

10.1182/blood.V128.22.163.163

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

163

引用

页数：7

共 49 条

[1] ELTROMBOPAG IN COMBINATION WITH AZACITIDINE FOR FIRST-LINE TREATMENT OF MDS PATIENTS WITH THROMBOCYTOPENIA: THE RANDOMIZED, PLACEBO-CONTROLLED, PHASE III, SUPPORT STUDY
Dickinson, M.
Cherif, H.
Fenaux, P.
Mittelman, M.
Verma, A.
Portella, M. S. O.
Burgess, P.
Platzbecker, U.
LEUKEMIA RESEARCH, 2017, 55 : S23 - S24
[2] RANDOMIZED, PLACEBO (PBO)-CONTROLLED, PHASE I/II TRIAL OF THE THROMBOPOIETIN RECEPTOR AGONIST ELTROMBOPAG (EPAG) IN THROMBOCYTOPENIC PATIENTS WITH ADVANCED MYELODYSPLASTIC SYNDROMES (MDS)
Platzbecker, U.
Wong, R. S.
Araujo, S.
Feigert, J.
Bennett, J.
Messam, C.
Mannino, F.
Kamel, Y. Mostafa
Dougherty, S.
Chan, G.
Giagounidis, A.
HAEMATOLOGICA, 2015, 100 : 67 - 68
[3] A Randomized, Placebo-Controlled, Phase II Study of Pracinostat in Combination with Azacitidine (AZA) in Patients with Previously Untreated Myelodysplastic Syndrome (MDS)
Garcia-Manero, Guillermo
Berdeja, Jesus G.
Komrokji, Rami S.
Essell, James
Lyons, Roger M.
Maris, Michael
DeZern, Amy E.
Sekeres, Mikkael A.
Roboz, Gail J.
BLOOD, 2015, 126 (23)
[4] THROMBOPOIETIN RECEPTOR AGONIST ELTROMBOPAG FOR ADVANCED MDS OR AML AND SEVERE THROMBOCYTOPENIA: 12-WEEK, RANDOMIZED, PLACEBO-CONTROLLED, PHASE 2 ASPIRE STUDY
Mittelman, M.
Platzbecker, U.
Afanasyev, B.
Grosicki, S.
Wong, R. S.
Anagnostopoulos, A.
Brenner, B.
Denzlinger, C.
Rossi, G.
Nagler, A.
Garcia Delgado, R.
Stone, N.
Zhu, Z.
Kalambakas, S.
Selleslag, D.
HAEMATOLOGICA, 2016, 101 : 15 - 16
[5] PLACEBO-CONTROLLED, RANDOMIZED, PHASE I/II TRIAL OF THE THROMBOPOIETIN RECEPTOR AGONIST ELTROMBOPAG IN THROMBOCYTOPENIC PATIENTS WITH ADVANCED MYELODYSPLASTIC SYNDROMES OR ACUTE MYELOID LEUKEMIA
Platzbecker, U.
Wong, R.
Verma, A.
Abboud, C.
Araujo, S.
Chiou, T.
Feigert, J.
Yeh, S.
Goetze, K.
Gorin, N.
Greenberg, P.
Kambhampati, S.
Kim, Y.
Lee, J.
Lyons, R.
Ruggeri, M.
Santini, V.
Cheng, G.
Jang, J.
Chen, C.
Dougherty, S.
Mannino, F.
Kamel, Y.
Chan, G.
Arning, M.
Stone, N.
Giagounidis, A.
HAEMATOLOGICA, 2013, 98 : 455 - 455
[6] Eltrombopag for Low-Risk Myelodysplastic Syndromes With Thrombocytopenia: Interim Results of a Phase II, Randomized, Placebo-Controlled Clinical Trial (EQOL-MDS)
Oliva, Esther Natalie
Riva, Marta
Niscola, Pasquale
Santini, Valeria
Breccia, Massimo
Giai, Valentina
Poloni, Antonella
Patriarca, Andrea
Crisa, Elena
Capodanno, Isabella
Salutari, Prassede
Reda, Gianluigi
Cascavilla, Nicola
Ferrero, Dario
Guarini, Attilio
Tripepi, Giovanni
Ianni, Giuseppe
Russo, Emilio
Castelli, Andrea
Fattizzo, Bruno
Beltrami, Germana
Bocchia, Monica
Molteni, Alfredo
Fenaux, Pierre
Germing, Ulrich
Ricco, Alessandra
Palumbo, Giuseppe A.
Impera, Stefana
Di Renzo, Nicola
Rivellini, Flavia
Buccisano, Francesco
Stamatoullas-Bastard, Aspasia
Liberati, Anna Marina
Candoni, Anna
Delfino, Ilaria Maria
Arcadi, Maria Teresa
Cufari, Patrizia
Rizzo, Lorenzo
Bova, Irene
D'Errigo, Maria Grazia
Zini, Gina
Latagliata, Roberto
JOURNAL OF CLINICAL ONCOLOGY, 2023, 41 (28) : 4486 - +
[7] Randomized, Placebo-Controlled, Phase I/II Trial Of The Thrombopoietin Receptor Agonist Eltrombopag In Thrombocytopenic Patients With Advanced Myelodysplastic Syndromes Or Acute Myeloid Leukemia - A Subgroup Analysis Of Patients Receiving Concomitant Anticancer Therapy
Platzbecker, Uwe
Wong, Raymond S. M.
Verma, Amit
Abboud, Camille N.
Araujo, Sergio
Chiou, Tzeon-Jye
Feigert, John
Yeh, Su-Peng
Goetze, Katharina
Gorin, Norbert Claude
Greenberg, Peter L.
Kambhampati, Suman
Kim, Yoo Jin
Lee, Je-Hwan
Lyons, Roger M.
Ruggeri, Marco
Santini, Valeria
Cheng, Gregory
Jang, Jun Ho
Chen, Chien-Yuan
Dougherty, Souria Hasan
Mannino, Frank
Kamel, Yasser Mostafa
Chan, Geoffrey W.
Stone, Nicole L.
Giagounidis, Aristoteles
BLOOD, 2013, 122 (21)
[8] Phase III, Randomized, Placebo-Controlled Trial of CC-486 (Oral Azacitidine) in Patients With Lower-Risk Myelodysplastic Syndromes
Garcia-Manero, Guillermo
Santini, Valeria
Almeida, Antonio
Platzbecker, Uwe
Jonasova, Anna
Silverman, Lewis R.
Falantes, Jose
Reda, Gianluigi
Buccisano, Francesco
Fenaux, Pierre
Buckstein, Rena
Campelo, Maria Diez
Larsen, Stephen
Valcarcel, David
Vyas, Paresh
Giai, Valentina
Oliva, Esther Natalie
Shortt, Jake
Niederwieser, Dietger
Mittelman, Moshe
Fianchi, Luana
La Torre, Ignazia
Zhong, Jianhua
Laille, Eric
de Menezes, Daniel Lopes
Skikne, Barry
Beach, C. L.
Giagounidis, Aristoteles
JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (13) : 1426 - +
[9] Treatment with the Thrombopoietin (TPO)-Receptor Agonist Romiplostim in Thrombocytopenic Patients (Pts) with Low or Intermediate-1 (Int-1) Risk Myelodysplastic Syndrome (MDS): Results of a Randomized, Double-Blind, Placebo(PBO)-Controlled Study
Giagounidis, Aristoteles
Mufti, Ghulam J.
Kantarjian, Hagop M.
Fenaux, Pierre
Sekeres, Mikkael A.
Szer, Jeffrey
Kuendgen, Andrea
Platzbecker, Uwe
Gaidano, Gianluca
Jedrzejczak, Wieslaw
Hu, Kuolung
Yang, Allen S.
Jun, Susie
BLOOD, 2011, 118 (21) : 57 - 58
[10] Efficacy and Safety of Eltrombopag for the Treatment of Thrombocytopenia of Low and Intermediate-1 IPSS Risk Myelodysplastic Syndromes: Interim Analysis of a Prospective, Randomized, Single-Blind, Placebo-Controlled Trial (EQoL-MDS)
Oliva, Esther Natalie
Santini, Valeria
Zini, Gina
Palumbo, Giuseppe A.
Poloni, Antonella
Cortelezzi, Agostino
Voso, Maria Teresa
Molteni, Alfredo
Sanpaolo, Grazia
Marino, Antonio
Roda, Filippo
Alati, Caterina
Ronco, Francesca
Di Raimondo, Francesco
Leoni, Pietro
Alimena, Giuliana
Finotto, Silvia
Latagliata, Roberto
Nobile, Francesco
BLOOD, 2012, 120 (21)

← 1 2 3 4 5 →