A general mechanism for selective inhibition of cyclooxygenase-1 and-2 as probed by a series of diaryl heterocycles

被引：0
|
作者：
Walker, MC [1 ]
Gierse, JK [1 ]
Koboldt, CM [1 ]
Moreland, KT [1 ]
Isakson, PC [1 ]
Seibert, K [1 ]
机构：
[1] Monsanto Co, Searle Discovery Res, St Louis, MO 63198 USA
来源：
FASEB JOURNAL | 1999年 / 13卷 / 07期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：A1352 / A1352
页数：1
相关论文
共 50 条
  • [1] Tests for cyclooxygenase-1 and-2 inhibition
    Pairet, M
    Van Ryn, J
    [J]. CLINICAL SIGNIFICANCE AND POTENTIAL OF SELECTIVE COX-2 INHIBITORS, 1998, : 19 - 30
  • [2] Effect of selective cyclooxygenase-1 and-2 inhibition on intimal hyperplasia in a rat model of balloon angioplasty
    Connolly, E
    Austin, L
    Desmond, FJ
    Orina, BA
    [J]. CIRCULATION, 2000, 102 (18) : 176 - 177
  • [3] Immunoexpression of cyclooxygenase-1 and-2 in ulcerative colitis
    Paiotti, A. P. R.
    Neto, R. Artigiani
    Forones, N. M.
    Oshima, C. T. F.
    Miszputen, S. J.
    Franco, M.
    [J]. BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, 2007, 40 (07) : 911 - 918
  • [4] Expression of cyclooxygenase-1 and-2 in gastric ulcer
    Chan, FKL
    To, KF
    Cheng, ACL
    Ng, YB
    Lee, TL
    Chung, SCS
    Sung, JY
    [J]. GUT, 1999, 45 : A49 - A50
  • [5] Cyclooxygenase-1 and-2 in human testicular tumours
    Hase, T
    Yoshimura, R
    Matsuyama, M
    Kawahito, Y
    Wada, S
    Tsuchida, K
    Sano, H
    Nakatani, T
    [J]. EUROPEAN JOURNAL OF CANCER, 2003, 39 (14) : 2043 - 2049
  • [6] SELECTIVE-INHIBITION OF CYCLOOXYGENASE-2 - DIARYL HETEROCYCLES VS CLASSICAL NSAIDS
    PINTO, DJ
    PITTS, WJ
    COPELAND, RA
    COVINGTON, MB
    TRZASKOS, J
    MAGOLDA, R
    [J]. MEDICINAL CHEMISTRY RESEARCH, 1995, 5 (05) : 394 - 398
  • [7] Expression of cyclooxygenase-1 and-2 in canine nasal carcinomas
    Borzacchiello, G
    Paciello, O
    Papparella, S
    [J]. JOURNAL OF COMPARATIVE PATHOLOGY, 2004, 131 (01) : 70 - 76
  • [8] Cyclooxygenase-1 and-2 in synovial tissues of arthritis patients
    Crofford, LJ
    [J]. CLINICAL SIGNIFICANCE AND POTENTIAL OF SELECTIVE COX-2 INHIBITORS, 1998, : 41 - 48
  • [9] Distinct expression of cyclooxygenase-1 and-2 in the human thymus
    Rocca, B
    Maggiano, N
    Habib, A
    Petrucci, G
    Gessi, M
    Fattorossi, A
    Lauriola, L
    Landolfi, R
    Ranelletti, FO
    [J]. EUROPEAN JOURNAL OF IMMUNOLOGY, 2002, 32 (05) : 1482 - 1492
  • [10] Cyclooxygenase-1 and-2 are expressed by human T cells
    Pablos, JL
    Santiago, B
    Carreira, PE
    Galindo, M
    Gomez-Reino, JJ
    [J]. CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 1999, 115 (01): : 86 - 90
12345