Synthesis of acyclo C-Nucleosides of H1-antihistaminic 4-substituted [1,2,4]triazolo[4,3-a]quinazolin-5(4H)-ones

被引：3

作者：

Shawali, Ahmad S. ^{[1
]}

Hassaneen, Hamdi M. ^{[1
]}

Shurrab, Nabil Kh. ^{[1
]}

机构：

[1] Cairo Univ, Fac Sci, Dept Chem, Giza, Egypt

来源：

JOURNAL OF CHEMICAL RESEARCH | 2008年 / 07期

关键词：

aldoses; C-nucleosides; 1,5-electrocyclisation; nitrilimines;

D O I：

10.3184/030823408X333454

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two series of aldose N-(3-substituted-4-oxo-3,4-dihydroquinazolin-2-yl)hydrazones were prepared by the reaction of each of the aldoses with the appropriate 2-hydrazino-3-substituted-quinazolin-4(3H)-ones. Oxidative cyclisation of these aldose hydrazones with ferric chloride in ethanol yielded the title acyclo C-nucleosides.

引用

页码：425 / 428

页数：4

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[1] Synthesis of acyclo C-Nucleosides of H1-antihistaminic 4-substituted [1,2,4]triazolo[4,3-a]quinazolin-5(4H)-ones (July, pg 425, 2008)
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