Eradication of initial pseudomonas aeruginosa colonization in patients with cystic fibrosis

被引:0
|
作者
Griese, M [1 ]
Müller, I [1 ]
Reinhardt, D [1 ]
机构
[1] Univ Munich, Dr Von Haunerschen Kinderspital, Kinderklin & Kinderpoliklin, D-80336 Munich, Germany
关键词
Pseudomonas aeruginosa; infection; treatment; antibodies; inhaled tobramycin;
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The optimal treatment for the eradication of initial P. aeruginosa infection in CF is still unclear. Recently long-term inhaled tobramycin has been proposed. Here we report the results with brief inhaled and/or systemic anti-pseudomonal treatments. Initial P. aeruginosa colonization was successfully eradicated as demonstrated by negative repetitive throat cultures or sputa and serum antipseudomonal antibodies in 15 of 17 patients for at least two years. Randomized, controlled trials are urgently needed to define the optimal protocol for the eradication of P. aeruginosa.
引用
收藏
页码:79 / 80
页数:2
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