Anti-Leukemia Activity of Alloreactive NK Cells in Haploidentical HSCT in Pediatric Patients: Re-Defining the Role of Activating and Inhibitory KIR

被引：0
|
作者：
Pende, Daniela [1 ]
Marcenaro, Stefania [2 ]
Falco, Michela [3 ]
Martini, Stefania [1 ]
Bernardo, Maria Ester
Montagna, Daniela [4 ]
Romeo, Elisa [3 ]
Martinetti, Myriam [5 ]
Maccario, Rita [6 ]
Mingari, Maria Cristina [2 ]
Moretta, Lorenzo [2 ,3 ]
Locatelli, Franco
Morena, Alessandro [2 ]
机构：
[1] Ist Nazl Ric Canc, I-16132 Genoa, Italy
[2] Univ Genoa, Dipartimento Med Sperimentale, Genoa, Italy
[3] Ist Giannina Gaslini, I-16148 Genoa, Italy
[4] Univ Pavia, Policlin San Matteo, Fdn IRCCS, Dipartimento Sci Pediat, I-27100 Pavia, Italy
[5] Univ Pavia, Fdn IRCCS Policlin, Lab Tipizzaz Tissutale, I-27100 Pavia, Italy
[6] Univ Pavia, Policlin San Matteo, Fdn IRCCS, Lab Trapianto Midollo Osseo & Oncoematol, I-27100 Pavia, Italy
来源：
BLOOD | 2008年 / 112卷 / 11期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：1032 / 1033
页数：2
相关论文
共 9 条
  • [1] Alloreactive NK Cells Exert Anti-leukemia Activity in Haplo-HSCT to Pediatric Patients: Revised Role of Activating and Inhibitory KIR
    Marcenaro, Stefania
    Martini, Stefania
    Falco, Michela
    Bernardo, Maria Ester
    Locatelli, Franco
    Moretta, Alessandro
    Moretta, Lorenzo
    Pende, Daniela
    CLINICAL IMMUNOLOGY, 2009, 131 : S29 - S29
  • [2] Alloreactive NK Cells Exert Anti-leukemia Activity in Haplo-HSCT to Pediatric Patients: Revised Role of Activating and Inhibitory KIR
    Marcenaro, Stefania
    Martini, Stefania
    Falco, Michela
    Bernardo, Maria Ester
    Locatelli, Franco
    Moretta, Alessandro
    Moretta, Lorenzo
    Pende, Daniela
    CLINICAL IMMUNOLOGY, 2009, 131 : S51 - S51
  • [3] Anti-leukemia activity of alloreactive NK cells in KIR ligand-mismatched haploidentical HSCT for pediatric patients: evaluation of the functional role of activating KIR and redefinition of inhibitory KIR specificity
    Pende, Daniela
    Marcenaro, Stefania
    Falco, Michela
    Martini, Stefania
    Bernardo, Maria Ester
    Montagna, Daniela
    Romeo, Elisa
    Cognet, Celine
    Martinetti, Miryam
    Maccario, Rita
    Mingari, Maria Cristina
    Vivier, Eric
    Moretta, Lorenzo
    Locatelli, Franco
    Moretta, Alessandro
    BLOOD, 2009, 113 (13) : 3119 - 3129
  • [4] DONOR-DERIVED ANTI-LEUKEMIA CTLS FOR THE CONTROL OF LEUKEMIA RELAPSE IN HIGH-RISK PEDIATRIC PATIENTS GIVEN HAPLOIDENTICAL HSCT
    Tanzi, Matteo
    Montini, Enrica
    Rumolo, Agnese
    Comoli, Patrizia
    Moretta, Antonia
    Giorgiani, Giovanna
    Recupero, Santina
    Mina, Tommaso
    Acquafredda, Gloria
    Rotella, Jessica
    Boghen, Stella
    Zecca, Marco
    Montagna, Daniela
    BONE MARROW TRANSPLANTATION, 2023, 58 (SUPP1) : 238 - 239
  • [5] Temporal, quantitative and functional characteristics of Single-KIR positive alloreactive NK cell recovery account for impaired graft versus leukemia activity after haploidentical HSCT
    Vago, Luca
    Fomot, Barbara
    Zino, Elisabetta
    Di Terlizzi, Simona
    Stanghellini, Maria T. Lupo
    Crocchiolo, Roberto
    Pema, Serena K.
    Bondanza, Attilio
    Mazzi, Benedetta
    Peccatori, Jacopo
    Roncarolo, Maria G.
    Bordignon, Claudio
    Bonini, Chiara
    Ciceri, Fabio
    Fleischhauer, Katharina
    BLOOD, 2007, 110 (11) : 961A - 961A
  • [6] Long-lived donor-derived human memory-like NK cells with potent anti-leukemia activity as a novel cell therapy approach to control leukemia relapse after haploidentical HSCT
    Tanzi, Matteo
    Consonni, Michela
    Ferulli, Federica
    Turin, Ilaria
    Montini, Enrica
    Boghen, Stella
    Acquafredda, Gloria
    Compagno, Francesca
    Dellabona, Paolo
    Casorati, Giulia
    Zecca, Marco
    Montagna, Daniela
    BONE MARROW TRANSPLANTATION, 2018, 53 : 42 - 43
  • [7] ROLE OF ACTIVATING AND INHIBITORY KIR-BASED EDUCATION OF NK CELLS IN VIRAL INFECTIONS IN PATIENTS GIVEN T CELL REPLETE UNRELATED HEMATOPOIETIC TRANSPLANT
    Nowak, Jacek
    Graczyk-Pol, Elzbieta
    Gwozdowicz, Sawomir
    Mika-Witkowska, Renata
    Rogatko-Koros, Marta
    Nestorowicz, Klaudia
    Szlendak, Urszula
    Pawliczak, Daria
    Zubala, Marta
    Malinowska, Agnieszka
    Hutnik, Emilia
    Kaczmarek, Beata
    HLA, 2019, 93 (05) : 277 - 278
  • [8] Human Cytokine-Induced Memory-like NK Cells Exhibit in Vivo Anti-Leukemia Activity in Xenografted NSG Mice and in Patients with Acute Myeloid Leukemia (AML)
    Romee, Rizwan
    Maximillian, Rosario
    Berrien-Elliott, Melissa M.
    Wagner, Julia A.
    Jewell, Brea A.
    Schappe, Timothy
    Leong, Jeffrey W.
    Schneider, Stephanie E.
    Willey, Sarah
    Fehniger, Todd A.
    BLOOD, 2015, 126 (23)
  • [9] Production of donor-derived cytotoxic T lymphocytes with potent anti-leukemia activity for adoptive immunotherapy in high-risk pediatric patients given haploidentical hematopoietic stem cell transplantation
    Tanzi, Matteo
    Montini, Enrica
    Rumolo, Agnese
    Moretta, Antonia
    Comoli, Patrizia
    Acquafredda, Gloria
    Rotella, Jessica
    Taurino, Gloria
    Compagno, Francesca
    Delle Cave, Francesco
    Perotti, Cesare
    Marseglia, Gian Luigi
    Zecca, Marco
    Montagna, Daniela
    CYTOTHERAPY, 2024, 26 (08) : 878 - 889
1